Role of satellite cells versus myofibers
in muscle hypertrophy induced by inhibition of the myostatin/activin signaling pathway.
Moreover, H&E-stained cross sections of soleus muscles showed the typical signs of injury and regeneration on day 5 after glycerol injection, as indicated by chronic inflammation (infiltration of mononucleated cells) and newly formed myofibers
with centralized nuclei, as well as nearly complete regeneration on day 12, as indicated by the largely restored muscle architecture (Figure 9A).
A histochemical study of myofiber
types in the serratus ventralis thoracis muscle of sheep durant of growth.
Histology confirmed that myoblast engraftment and myofiber
formation occurred, but further research is needed to assess whether the transplant procedure imparts any functional improvement, the researchers said.
Studies so far have demonstrated that desmin is absolutely necessary for muscle differentiation in vitro and plays an essential role in the maintenance of myofibril, myofiber
, and whole muscle structural and functional integrity.
Almost all patients develop progressive muscular weakness and atrophy that begin at a young age in association with myofiber
degeneration and necrosis (3-5).
In the mdx mouse, an animal model with a genetic defect identical to DMD, the company showed muscle tissue preservation on histopathology and a statistically significant increase in myofiber
(muscle fibers) diameter in treated vs non-treated mice.
However, this is not a universal finding and others have noted that sex differences in load-induced myofiber
hypertrophy among older adults cannot be explained by levels of circulating IGF-1 , a finding that may be explained by the effects of age on IGF-1 .
Few shrimp exhibited angular, wedge-shaped foci of myofiber
degeneration with fibrosis.
In this study, our results of myofiber
transverse section microstructure (Figure 1 and Table 2) support the findings of Ockerman and Organisciak (1978), Pietrasik and Shand (2004) and Siro et al.
compared voluntary and NMES-induced contractions and their resultant effect on delayed-onset muscle soreness and specific myofiber
damage leads to the release of nitric oxide, which mediates the release of active hepatocyte growth factor from the heparin sulfate chains on the extracellular matrix and surrounding myofibers