Intracardiac catecholamine discharge, coagulated myocytolysis
, contraction band necrosis, calcium discharge, and reperfusion injury are the possible mechanisms of cardiac dysfunction (6,7,8).
In terms of the myocardium morphology, 3 hours after resuscitation, the control group displayed myocytolysis
and transverse contraction bands.
Tissue analysis reveals the presence of chronic myocarditis, myocytolysis
, and an intense interstitial fibrosis, as the result of a combination of persistent parasitism, microvascular inflammation, neurogenic dysfunction, and autoimmune responses .
The occlusion of MCA in rats determined myocytolysis
, increased blood pressure and circulating norepinephrine levels, especially when right insular cortex was involved .
Studies (64,66) have shown that uterine artery embolization causes hyaline (ischemic)-type necrosis, often associated with vacuolar change secondary to myocytolysis
. It should be pointed out that if coagulative tumor cell necrosis is present in a leiomyoma post therapy, other histologic features of malignancy should be evaluated carefully.
Neurogenic cardiac injury, in contrast, is predominantly myofibrillar degeneration or myocytolysis
that is transient and distinct from myocardial necrosis.
Contraction band necrosis is also known as myofibrillar degeneration and coagulative myocytolysis
It is believed that the virus has a direct cytotoxic effect on the cardiac myocytes causing myocytolysis
, necrosis, and oedema.
Pathogenesis of isoproterenol-induced myocardial lesions: its relation to human and coagulative myocytolysis
. Cardiology 63, 139-151.
Cardiac sequelae including myocytolysis
, serum enzyme elevations and arrhythmias are known to develop in a portion of stroke patients.
(2010) after injecting venom were myocytolysis
(lysis of myocytes), coagulation necrosis, focal hemorrhage, thrombus formation both in myocardium and on endocardial surfaces.
Necropsy findings showed mainly eosinophilic infiltrates with myocytolysis
(consistent with an acute drug reaction).