Secondary endpoints included median percent change from baseline and 50% responder rate for absence and myoclonic
Key clinical point: Patients with juvenile myoclonic
epilepsy generally have a long-term quality of life that is generally equal to or better than patients with childhood or juvenile absence epilepsy.
Dosing solely at night often effective for myoclonic
jerks (and may be first choice)
Acute phase: A more rapidly progressive phase characterized by severe confusion, hallucinations, ataxia, dysarthria, myoclonic
jerks and rarely seizures.
We suggest that FOUR score will be helpful in estimating prognosis in stroke patients in particular since it does not depend on verbal responses, provides information about brainstem reflexes and includes the evaluation of myoclonic
Directed questioning is essential to reveal unreported or unrecognised seizures such as myoclonic
jerks and absences.
THIS strange falling sensation and muscle twitch is known as a hypnagogic myoclonic
twitch or " hypnic jerk" If this has happened to you on more than one occasion, don't worry, you are not alone.
Today her mum Mandy Flynn opened her heart to the Gazette to raise awareness of severe myoclonic
epilepsy - also known as Dravet Syndrome.
The movement, known as a sleep start, or hypnic or myoclonic
jerk, usually happens just before deeper sleep.
Other types of generalized seizures are: tonic seizures which involve muscie rigidity but are not followed by a clonic phase; clonic seizures which involve violent rhythmic contractions but is not preceded by tonic phase; myoclonic
seizures in which a person has brief involuntary jerking of the torso or extremities; and atonic seizures in which the skeletal muscles lose all tone causing the person to suddenly drop to the floor.
5] Nonstandard abbreviations: LGMD, limb girdle muscular dystrophy; SCA, spinocerebellar ataxia; MELAS, mitochondrial encephalopathy, lactic acidosis and stroke-like episodes; MERRF, myoclonic
epilepsy with ragged-red fibers; NARP, neurogenic muscle weakness, ataxia and retinitis pigmentosa syndrome; CMT, Charcot-Marie-Tooth.
These include benign rolandic epilepsy, juvenile myoclonic
epilepsy and temporal lobe epilepsy.