myocardial perfusion imaging


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imaging

 [im´ij-ing]
the production of diagnostic images, e.g., radiography, ultrasonography, or scintigraphy.
digital subtraction imaging a technique in radiography in which electronic subtraction allows the visualization of individual images; see also digital subtraction angiography.
electrostatic imaging a method of visualizing deep structures of the body, in which an electron beam is passed through the patient and the emerging beam strikes an electrostatically charged plate, dissipating the charge according to the strength of the beam. A film is then made from the plate.
gated cardiac blood pool imaging equilibrium radionuclide angiocardiography.
horizontal beam imaging a grid positioning technique in radiology in which the grid cassette is positioned with its lead lines perpendicular to the floor.
hot spot imaging (infarct avid imaging) infarct avid scintigraphy.
magnetic resonance imaging see magnetic resonance imaging.
myocardial perfusion imaging myocardial perfusion scintigraphy.

myocardial perfusion imaging

A technique in which the regional distribution of blood throughout the myocardium, is determined by injecting a radiopharmaceutical–eg, 201Tl. or 99mTc and capturing images with a gamma–scintillation camera; by determining blood and oxygen distribution, MPI informs on the hemodynamics and functional effect of coronary arterial stenosis

myocardial perfusion imaging

Abbreviation: MPI
The use of radioactive isotopes, such as 201Tl or 99mTc sestamibi, to gauge the blood supply and viability of the regions or walls of the heart. MPI is frequently used to assess patients with coronary artery disease, often in conjunction with exercise tolerance tests. A patient with a coronary artery that is almost totally blocked may take up only a small quantity of radioisotope during exercise but much more of the tracer after several hours of rest. By contrast, heart muscle that is fed by a completely blocked artery will take up no radioisotope either during or after exercise.
See also: imaging
References in periodicals archive ?
Prognostic significance of dipyridamole-induced ST depression in patients with normal 82Rb PET myocardial perfusion imaging.
The findings demonstrated PET myocardial perfusion imaging with flurpiridaz F 18 provided superior image quality, diagnostic certainty, and diagnostic performance for detecting CAD compared to SPECT MPI, the current standard for the non-invasive detection of CAD.
Oral Session: "Comparison of flurpiridaz F 18 PET injection and Tc-99m labeled SPECT myocardial perfusion imaging for identifying severity and extent of stress induced myocardial ischemia in Phase 2 clinical trials," Tuesday, June 7, 5:30 p.
24) These improvements result in accurate myocardial perfusion imaging without the limitation of different portions of the myocardium being scanned at different times in relation to the contrast bolus.
The unexpected finding suggests that a substantial proportion of patients with type 2 diabetes and silent myocardial ischemia have the potential for improvement of stress myocardial perfusion imaging abnormalities with medical management, Dr.
Results from this Phase 2 trial show that PET myocardial perfusion imaging with flurpiridaz F 18 demonstrate a strong safety profile and is superior to SPECT imaging with respect to the quality of rest and stress images, certainty of image interpretation, and diagnostic performance as measured by standard ROC analysis for detecting CAD," said Dr.
Myocardial perfusion imaging (MPI) is primarily performed on widely available single photon emission computed tomography (SPECT) systems.
The results validate a long-standing practice at Massachusetts General Hospital, Boston, where supplemental arm exercise with light weights--not arm exercise with squeeze balls and not a treadmill walk--has been used for a decade to prevent adenosine-related side effects during myocardial perfusion imaging.
PET myocardial perfusion imaging with flurpiridaz F 18 has the potential to better evaluate patients with known or suspected coronary artery disease than SPECT imaging, and we look forward to initiating Phase 3 clinical trials of this important new clinical tool in the second quarter of this year.
The ASPIRE study (A Randomized, Controlled, Parallel Group, Multi-center Study To Evaluate The Efficacy And Safety Of Ad5FGF-4 Using Adenosine SPECT Myocardial Perfusion Imaging In Patients With Stable Angina Pectoris) is expected to enroll approximately 100 men and women with myocardial ischemia due to coronary artery disease at up to six leading medical centers in Moscow.
Several clinical reports have endorsed the accuracy of dynamic myocardial perfusion imaging at 1.

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