myeloproliferative disorders


Also found in: Dictionary, Thesaurus, Legal, Encyclopedia.

myeloproliferative

 [mi″ĕ-lo-pro-lif´er-ah″tiv]
pertaining to or characterized by abnormal proliferation of bone marrow constituents.
myeloproliferative disorders a group of usually neoplastic diseases, which may be related histogenetically by a common multipotential stem cell; it includes among others acute myelogenous leukemia, chronic granulocytic leukemia, acute and chronic myelomonocytic leukemias, and polycythemia vera. An interrelationship with the lymphoproliferative disorders is thought to exist.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

myeloproliferative disorders

A group of diseases featuring excessive production of blood cells by bone marrow precursors. The group includes POLYCYTHAEMIA VERA, chronic myelogenous LEUKAEMIA, platelet over-production (essential THROMBOCYTHAEMIA) and idiopathic MYELOFIBROSIS. A common feature is clonal haematopoiesis probably involving the haematopoietic stem cell. A high proportion of patients with these disorders have a mutation of the Janus kinase 2 (JAK2) gene on the short arm of chromosome 9.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005
Mentioned in ?
References in periodicals archive ?
Only 1 study has provided an estimate of the frequency of the NS-related myeloproliferative disorder (NS/MPD) or monocytosis of NS [10].
Pulmonary Vasculitis and a Horseshoe Kidney in Noonan Syndrome
Majority of patients with noncirrhotic, nonmalignant PVT have better prognosis compared to patients with cirrhosis-associated PVT and PVT associated with advanced malignancy or rapidly progressing myeloproliferative disorder. In those cases, survival is limited by underlying disease rather than PVT itself.
Sport-Related Portal Vein Thrombosis: An Unusual Complication
Scapin et al., "Heparin-induced thrombocytopenia in patients with philadelphia-negative myeloproliferative disorders and unusual splanchnic or cerebral vein thrombosis," Acta Haematologica, vol.
Anti-Platelet Factor 4/Heparin Antibody Formation Occurs Endogenously and at Unexpected High Frequency in Polycythemia Vera
They most commonly arise in patients previously diagnosed with a myeloproliferative disorder, but they can be the presenting sign of cancer or even precede the onset of hematogenous disease by months to years.
Myeloid sarcomas of the head and neck in pediatric patients with myeloid leukemia
ETV6-ACSL6 fusion is a rare abnormality that is associated with myeloproliferative disorders, myelodysplasia, or acute myeloid leukemia with eosinophilia or basophilia.
Myeloid neoplasms with t(5;12) and ETV6-ACSL6 gene fusion, potential mimickers of myeloid neoplasm with PDGFRB rearrangement: case report with imatinib therapy and review of the literature
Myeloproliferative disorders in equines species are rarely reported (SEARCY & ORR, 1981; McCLURE et al., 0001; TAINTOR, 0010).
Equine acute erythroid leukemia/Leucemia eritroide aguda em equino
[USPRwire, Tue Nov 03 2015] GlobalData's clinical trial report, "Myeloproliferative Disorders Global Clinical Trials Review, H2, 2015" provides an overview of Myeloproliferative Disorders clinical trials scenario.
New Market Report: Myeloproliferative Disorders Global Clinical Trials Review, H2, 2015
(2) Leukemogenic risk of Hydroxyurea is extrapolated from its reported risk in myeloproliferative disorders. (3) Hematologic Malignancies in patient with sickle cell anemia are rare.
Possibility of Leukogenicity effect of long term use of hydroxyurea in sickle cell Anaemia
The causes of thrombocytosis could be multiple such as myeloproliferative disorders ,reactive thrombocytosis, Post splenectomy and hyposplenism.2
Thrombocytosis in a patient with systemic lupus
Congenital leukaemia and the neonatal myeloproliferative disorders associated with Down's syndrome.
A newborn with subcutaneous nodules/Deri alti nodulleri olan yenidogan
Hematologic malignancies can be categorized as myeloid neoplasms, lymphoid neoplasms (leukemias and lymphomas), and myeloproliferative disorders.
Types of blood cancers--and the new molecular diagnostics
A prospective evaluation of primary myeloproliferative disorders. Gastroenterology 1988;94:1063-9.
CAVERNOUS TRANSFORMATION OF PORTAL VEIN - A RARE CAUSE OF MASSIVE HEPATOMEGALY

Medical browser ?
Full browser ?