myeloma

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Related to myelomata: myeloma

myeloma

 [mi″ĕ-lo´mah]
1. a tumor composed of plasma cells of the type normally found in the bone marrow.
giant cell myeloma giant cell tumor (def. 1).
multiple myeloma see multiple myeloma.
plasma cell myeloma multiple myeloma.
solitary myeloma a variant of multiple myeloma in which there is a single localized tumor focus. Called also plasma cell tumor.

my·e·lo·ma

(mī'ĕ-lō'mă),
1. A tumor composed of cells derived from hemopoietic tissues of the bone marrow.
2. A plasma cell tumor.
[myelo- + G. -oma, tumor]

myeloma

(mī′ə-lō′mə)
n. pl. myelo·mas or myelo·mata (-mə-tə)
A malignant tumor formed by the cells of the bone marrow.

my′e·lo′ma·toid′ (-toid′) adj.

myeloma

Malignant plasmacytoma, multiple myeloma, multiple plasmacytoma of bone, myelomatosis, plasma cell myeloma Hematology A neoplastic proliferation of plasma cells in BM and extramedullary sites; if circumscribed, plasmacytoma Epidemiology MM comprises 10% of hematopoietic malignancies, causing 10,000 deaths/yr–US; ↑ with age; black:white 2:1 Clinical As the myeloma cells proliferate in BM, they cause osteolysis, resulting in pathologic fractures and industrial strength pain, anorexia, nausea, thirst, fatigue, muscle weakness, restlessness, confusion; BM replacement by neoplastic plasma cells results in ↑ infections and anemia due to displacement of normal WBCs, and erythroid series; excess Igs in circulation plug up renal tubules Lab Monoclonal Igs, often light chains, in serum, urine; ↑ Ca2+; normal PO4, normal alk phos Complications Painful pathologic fractures, anemia, hypercalcemia, renal failure, recurrent bacterial infections Treatment 1º chemotherapy: Melphalan and prednisone; VAD–vincristine, Adriamycin, dexamethasone in new cases; IFN-α has been used for maintenance; myeloablative therapy, allogeneic BMT from HLA-matched siblings. See Clear cell, myeloma, Indolent myeloma, Myeloma kidney, Solitary myeloma.

my·e·lo·ma

(mī'ĕ-lō'mă)
1. A tumor composed of cells derived from hemopoietic tissues of the bone marrow.
2. A plasma cell tumor.
[myelo- + G. -oma, tumor]

myeloma

A tumour derived from a lymphocyte. See LYMPHOMA, MYELOMATOSIS.

myeloma

a cancerous tumour of the bone marrow.

Myeloma

A tumor that originates in bone marrow and usually spreads to more than one bone.

my·e·lo·ma

(mī'ĕ-lō'mă)
1. A tumor composed of cells derived from hemopoietic tissues of bone marrow.
2. A plasma cell tumor.
[myelo- + G. -oma, tumor]

Patient discussion about myeloma

Q. Multiple Myeloma what and how is it treated and what is MGUF

A. Were you referring by any chance to MGUS (monoclonal gammopathy of unknown significance)? It's a condition that resembles myeloma but is much more widespread and by itself isn't considered malignant. It may, however, deteriorate to multiple myeloma over the years.

Myeloma is treated with chemotherapy of various kinds, and sometimes with bone marrow transplantation with the patients own bone marrow.

You may read more here:
www.nlm.nih.gov/medlineplus/multiplemyeloma.html

More discussions about myeloma