myeloma cell


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Related to myeloma cell: hybridoma

myeloma cell

A cell present in the bone marrow of patients with multiple myeloma.
See also: cell
References in periodicals archive ?
Flow cytometry in MM is beneficial in detecting malignant plasma cells and prognostic markers and monitoring the development and differentiation of myeloma cells.
We are committed to developing PVX-410, which is a therapeutic cancer vaccine developed to target multiple myeloma cells," said Doris Peterkin, Chief Executive Officer of OncoPep.
The poster on abstract #2914, The effect of ICAM-1 Antibody Therapy in the SCID-Hu Mouse Model Using Primary Myeloma Cells, is accessible on the BioInvent website (www.
Researchers at Dana-Farber Cancer Institute in collaboration with MannKind Corporation (Nasdaq:MNKD) generated results confirming that targeting the unfolded protein response (UPR) through the XBP-1 pathway impacts the survival of myeloma cells, suggesting a novel therapeutic strategy in multiple myeloma.
When myeloma cells were pretreated in vitro with imetelstat for two weeks and subsequently implanted in mice given no further treatment, the development of new tumors was significantly reduced, leading to increased survival of the animals compared to controls implanted with untreated myeloma cells.
Professor Stig Linder at Karolinska Institutet's Department of Oncology-Pathology, said that the discovery that their substance works on multiple myeloma cells resistant to conventional therapy is very promising for the future.
FAIM could thus be a therapeutic target in these patients, as drugs developed to target the molecule could destroy multiple myeloma cells and hence eradicate the cancer.
Instead, myeloma cells divide and expand within the bone marrow.
The nanoparticles are coated with a special peptide that targets a specific receptor on the outside of multiple myeloma cells.
The presented image showings heavily granulated myeloma cells, some with Auer rod-like inclusions.
Research investigators have identified molecular changes in multiple myeloma cells that activate an important biological pathway associated with cell growth and survival, thereby revealing potential new targets for drugs to treat this cancer.
The bone marrow on this patient showed a marked number of myeloma cells comprising 85% of total white cells.