Here, the researchers found that CD11b promotes development of myeloid cells
into one sub-type, the M1 macrophage, that functions appropriately to suppress tumor growth.
To promote the release of myeloid cells
from the bone marrow, macrophages were depleted using clodronate-encapsulated liposomes (purchased from http:// clodronateliposomes.com and supplied as a 5 mg/ml solution).
The understanding of the mechanisms by which TGF-[beta], MMPs, and tumor stroma-infiltrating myeloid cells
act may open new avenues which will develop more precise therapies for cancer treatment.
The heme enzyme myeloperoxidase (MPO), which is synthesized and secreted by neutrophils, monocytes, and other myeloid cells
, is an important source of oxidants.
Upon transplantation in inflammatory CNS disorders such as MS, TBI, SCI, and stroke, stem cells are likely to encounter myeloid cells
in both the CNS and periphery.
(18.) Ho DM, Wong TT, Guo WY, Chang KP, Yen .S1-1: Primary cerebellar extramedullary myeloid cell
tumor mimicking oligodendroglioma.
BCG inoculation or systemic irradiation of mice can result in inflammatory response, which will induce a group of abnormally proliferating myeloid cells
with the ability to inhibit the activation and function of cytotoxic T cells, known as natural suppressor cells .
This inflammation-related difference might be explained by the influence of inflammatory cytokines and mediators on the expression of myeloid cell
surface markers .
infiltration, including macrophage, monocyte and dendritic cells, is the key event in the pathogenesis of renal fibrosis.
KG1, a myeloid cell
line, was used as positive control, and calibrators were added to each plate.
GS was first coined by Rappaport, the other synonyms are chloroma, myeloblastoma, myelocytoma, extra medullary myeloid cell
On the other hand, the total PSA content in extracts from neoplastic myeloid cell
lines was significantly greater than in nondiseased PBLs (P = 0.0058, P = 0.0008, and P = 0.0004 for the HL-60, K562, and U937 cell lines, respectively).