myelodysplasic syndrome

A group of uncommon bone marrow disorders featuring reduced blood cell production with abnormal granular white cells, especially the neutrophil polymorphonuclear leukocytes, and resulting in ANAEMIA which is very difficult to treat. The neutrophils have reduced activity against organisms, so there is increased risk of infection. The syndrome affects the elderly and tends to progress to acute myeloid LEUKAEMIA. Bone marrow transplantation can produce long-term remission in younger patients.

Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005

Mentioned in ?

myelodysplasia

References in periodicals archive ?

Four years ago, bone marrow aspiration was performed for anemia etiology with the prediagnosis of myelodysplasic syndrome but it did not reveal any pathological findings.

Refractory hemolytic anemia due to severe swirling flow pattern in chronic mitral regurgitation after myxoma surgery/Miksoma cerrahisi sonrasi gelisen kronik mitral yetersizligine bagli siddetli "swirling" e bagli refrakter hemolitik anemi

Untener of Saginaw, Mich., will soon be undergoing treatment for myelodysplasic syndrome, a life-threatening form of leukemia.