myelodysplasia


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myelodysplasia

 [mi″ĕ-lo-dis-pla´zhah]
1. a neural tube defect consisting of defective development of part of the spinal cord. See also spina bifida.
2. dysplasia of myelocytes and other elements of the bone marrow, a chronic disease that in time may evolve into acute myelogenous leukemia. adj., adj myelodysplas´tic.

my·e·lo·dys·pla·si·a

(mī'ĕ-lō-dis-plā'zē-ă),
1. An abnormality in development of the spinal cord, especially the lower part of the cord.
2. Inappropriate term for spina bifida occulta.
Synonym(s): myelodyspoiesis
[myelo- + G. dys-, difficult, + plasis, a molding]

myelodysplasia

/my·elo·dys·pla·sia/ (-dis-pla´zhah)
1. a neural tube defect causing defective development of any part of the spinal cord.
2. dysplasia of myelocytes and other elements of the bone marrow.myelodysplas´tic

myelodysplasia

(mī′ə-lō-dĭs-plā′zhə)
n.
1. Abnormal development of the spinal cord.
2. Dysplasia of myelocytes and other cells in the bone marrow.

my′e·lo·dys·plas′tic (-plăs′tĭk) adj.

myelodysplasia

[mī′əlōdisplā′zhə]
Etymology: Gk, myelos + dys, bad, plassis, formation
1 a general designation for the defective development of any part of the spinal cord. The term is used primarily to describe abnormalities without gross superficial defects, especially of the lower segment, specifically spina bifida occulta.
2 dysplasia of the myelocytes and other elements in bone marrow.

myelodysplasia

Hematology Abnormal BM precursor cells, which may lead to CML. See Myelodysplastic syndrome Neurology A generic term for various developmental defects of the spinal cord and nerve roots–eg, myelomeningocele, sacral agenesis, spinal dysraphism and caudal regression syndrome;13 of infants with myelodysplasia develop external urethral sphincter dysfunction, often in the first 3 yrs of life, 12of which are permanent.

my·e·lo·dys·pla·si·a

(mī'ĕ-lō-dis-plā'zē-ă)
1. An abnormality in development of the spinal cord, especially the lower part of the cord.
2. A disorder within the bone marrow, characterized by the proliferation of abnormal stem cells, which have the potential of developing into a specific type of leukemia.
[myelo- + G. dys-, difficult, + plasis, a molding]

myelodysplasia

See MYELODYSPLASTIC SYNDROME.

myelodysplasia

1. defective development of the spinal cord.
2. disorders of myeloid cells of the bone marrow, either in number or degree of maturity.

hemopoietic myelodysplasia
includes myeloid metaplasia and myelofibrosis, refractory anemia with excess blast cells, and myelomonocytic leukemia.
myelodysplasia syndrome
qualitative defect in stem cells characterized by dysplastic hematopoietic cells and the presence of abnormal blast cells in the blood. There is also anemia, leukopenia and sometimes thrombocytopenia. See also myeloproliferative disease.
References in periodicals archive ?
Material and Methods: The study group was composed of 71 patients with myelodysplasia who were found to have significant bacteriuria (age: 8.
Aplastic anemia can occur as a consequence of immune dysregulation and toxic exposures, and as a manifestation of several hematologic disorders, including myelodysplasia and IBMFS.
This will distinguish the bone marrow disorders including acute leukaemia, myelofibrosis, bone marrow metastatic infiltration and myelodysplasia.
They claim that this discovery will improve the survival rates of leukemia and myelodysplasia patients.
Congenital erythropoietic porphyria associated with myelodysplasia presenting in a 72-year-old man: report of a case and review of literature.
TRIBUTE: Paul He was diagnosed with a rare form of blood cancer called myelodysplasia in 2010 and received many blood transfusions during his treatment for the disease.
Sunday, March 27, at the Center for Spiritual Living for Shelley Zavat of Eugene, who died March 1 of myelodysplasia, a rare blood disorder.
ESAs are not recommended to treat cancer-related anemia, except to prevent the need for transfusions in patients with lower-risk myelodysplasia.
Furthermore, a novel NA (I117M) substitution that may be associated with oseltamivir resistance (4,5) was detected in specimens from 1 patient (patient G) who had myelodysplasia and received oseltamivir and peramivir (Tables 1, 2).
Patients with acquired amegakaryocytic thrombocytopenia may have additional hematological abnormalities such as macrocytosis or dyserythropoiesis, abnormalities which may indicate potential future progression to aplastic anemia or myelodysplasia (8-10).
16-19) In 18 patients (33 clubfeet) with myelodysplasia, who were treated with casts and percutaneous Achilles tenotomies (PATs), 31 feet required no further treatment; the remaining two had posterior medial releases to correct recurrences.