myelination


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Related to myelination: demyelination

myelinization

 [mi″ĕ-lin″ĭ-za´shun]
production of myelin around an axon. Called also myelination.

my·e·li·na·tion

(mī'ĕ-li-nā'shŭn),
The acquisition, development, or formation of a myelin sheath around a nerve fiber.

myelination

(mī′ə-lə-nā′shən) also

myelinization

(-nĭ-zā′shən)
n.
The process of forming a myelin sheath.

my·e·li·na·tion

, myelinization (mī'ĕ-li-nā'shŭn, nī-zā'shŭn)
The acquisition, development, or formation of a myelin sheath around a nerve fiber.

Patient discussion about myelination

Q. What is Myelin?

A. As part of the nervous system, myelin lines nerve fibers to protect and insulate neurons. Myelin aids in the quick and accurate transmission of electrical current carrying data from one nerve cell to the next. When myelin becomes damaged, the process involves numerous health conditions, including multiple sclerosis.

Dysfunction in the myelin of nerve fibers causes the interruption of smooth delivery of information. Either nerve impulses can be slowed, such that we can't pull our hand away in time to avoid being burned, or mixed up, so we aren't able to determine if a pan is hot in the first place. This is akin to a pet chewing on a wire, causing the device to dysfunction. When problems arise in nerves of the PNS, neuropathy might result, and when injury affects the nerves of the CNS, multiple sclerosis is often diagnosed.

More discussions about myelination
References in periodicals archive ?
The effect of undernutrition and subsequent rehabilitation on myelination of rat brain as measured by its composition.
Furthermore, since NO at normal levels may promote myelination, [16] it may be inferred that pramiracetam, given the clinical trials that was performed, may actually be protective rather than damaging to neurons.
In particular, the protein PMP2 is a lipid transport protein of the SCs; it is also involved in myelination in the PNS.
Myelination is important in establishing connectivity in the growing brain by facilitating rapid and synchronized information transfer across the nervous system, which is essential to higher-order cognitive functions.
Thus, myelination is the most important factor for determining the latency of the VEP waveforms.
Myelination assessment and quantification To calculate the percentage of axonal myelination, a semi-automated computer platform, termed computer-assisted evaluation of myelin formation (CEM) (Kemian et al., 2015), which uses NIH Image J built-in tools as well as Math lab processing functions, was used.
For example, Alexander disease is a rare neurological disease with defect in myelination and it is known by seizure, developmental delay, intellectual disability, and spasticity, similar to PMD; however it has megalencephaly which is absent in PMD.
However, it demonstrated significant findings of delayed myelination of cerebral cortex, hypoplastic cerebellum, and cobblestone lissencephaly (Figures 1(a)-1(c)), all of which are well-characterized in WWS.
Glenn and Talbot [35] found that Gpr126 was essential for SCs to initiate myelination and addressed the role of Gpr126 signaling in myelin maturation and maintenance.
They found that daily consumption of fortification iron improved the iron status and VEP wave form pattern and suggested correction of ID in young women may partially restore impaired myelination of the visual pathway.
(11-16) At P7 in the mouse cerebellum, where PLD4-positive activated microglia are present, myelination is ongoing and apoptosis of excess oligodendrocytes occurs in addition to axonal pruning.
The pulsatile compression of TN cause demyelination resulting in pain of TGN which is relived after surgery as myelination occurs12,15.