MBP(redirected from myelin A1 protein)
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Abbreviation for major basic protein.
MBPA gene on chromosome 18q23 that encodes myelin basic protein, a major component of the myelin sheath of oligodendrocytes and Schwann cells, which is also present in the bone marrow and in the immune system where it induces T-cell proliferation.
Reduction in the surface charge of MBP may result in a weakened attachment to the myelin membrane and play a role in demyelinating diseases such as multiple sclerosis.