mutilating arthritis

mutilating arthritis

A generic term for end-stage joint destruction accompanied by osteolysis, which is typical of advanced psoriatic arthritis but may also occur in rheumatoid arthritis and in mixed connective tissue disease.

mutilating arthritis

Arthritis mutilans Rheumatology A generic term for end-stage joint destruction accompanied by osteolysis, seen advanced psoriatic arthritis, also in rheumatoid arthritis, mixed connective tissue disease. See Psoriatic arthritis, Rheumatoid arthritis.
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A patient with psoriatic monoarthritis may progress to polyarthritis or mutilating arthritis if neglected and early immunosuppressant or biological therapy is not instituted.
Patient RA4 had mutilating arthritis, with severe joint destruction.