As such, the populations with the highest EGFR-activating
mutation rate will also display the greatest detection rate for resistance mutations.
Analysis of 17Y-STRs Locus Specific
Mutation Rate. Using 100 Tanzanian father-son paired samples with confirmed paternity covering 1700 meioses were used to estimate 17YSTRs locus specific
mutation rate.
The EGFR
mutation rate is reported to be higher in nonsmokers than in smokers (6,7).
As depicted in Table 2 using any
mutation rate with number of generations of 1000, the energy reduction percentage is greater than 30%.
(34) This remarkable increase of M694V
mutation rate in AS patients compared to healthy individuals is associated with the fact that M694V mutation is seen in cases which show the highest penetration and most severe clinical course compared to other mutations.
If the pre-set parameters, such as crossover rate ([p.sub.c]) and
mutation rate ([p.sub.m]) are inappropriate, the fittest solution cannot be found.
Three simulation models developed for manufacturing environments were used for optimization and analysis of GA parameters (population size, number of generations, crossover rate and
mutation rate).
"The slower
mutation rate wasn't expected," says evolutionary biologist Adam Boyko of Cornell University.
The E148Q mutation of exon 2 was also evaluated, and its
mutation rate was reported as 12%.
It is outside the cell nuclear, and it is known that the
mutation rate in mtDNA is about 10 times that of the nuclear genes, and that on one section of the mitochondria, its control region, the
mutation rate is even one order higher.
Then the mutation process sets the mutation points for [S.sub.xy] according to
mutation rate [[delta].sub.xy].
• Precise selection of the average
mutation rate (number of changes per construct)
