References in periodicals archive
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One and the same device performs both dna isolation, Rt-pcr reaction for dna isolated, Mutation detection, And response to the mutated mutation.
RAS mutation detection methods included Sanger sequencing, qPCR assay, and Ion Torrent (Life Technologies/Thermo Fisher Scientific, Waltham, Massachusetts) next-generation sequencing.
US-based molecular diagnostics company DiaCarta has received CE-IVD approval for its new colorectal cancer test, ColoScape, a colorectal cancer mutation detection kit, the company said.
Transgenomic's ICE COLD-PCR technology delivers up to a 500-fold increase in mutation detection compared to most current methods, with levels of detection routinely achievable down to 0.
Out of these, the most important is the sensitivity and specificity of mutation detection method.
Its products are used in gene expression and copy number variation (CNV) analysis, mutation detection, SNP genotyping, platform, and laboratory environment.
It was reported yesterday that the agreement has been signed to co-market Archer's NGS assays and GenomOncology's data interpretation software for somatic mutation detection and reporting.
IDUS combined with brush cytology and K-ras + P53 gene mutation detection had obvious advantage in the sensitivity, accuracy and negative predictive value than any other joint detection and single detection (the advantage was more significant compared with IDUS + brush cytology or any single detection P < 0.
In this context, digital PCR has been used to detect BRAF (B-Raf proto-oncogene, serine/threonine kinase) mutations in ctDNA from melanoma patients treated with a BRAF inhibitor (2), showing that BRAF mutation detection in ctDNA is useful as a follow-up to treatment response in patients with advanced melanoma (2).
It out-licenses its transrenal technologies to extend oncogene mutation detection using urine as a sample.
Archer captures and amplifies only gene targets of interest and offers dramatic enhancements in scalability, mutation detection speed, complex mutation identification and reduced costs.
The overall sensitivity of mutation detection in rpoB gene was 88.
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