A cell that mutates
on an upper layer can form a bump that pushes altered cells down to the lowest layer, where they become "immortalized" as stem cells, says Portier, who adds that he believes "stem cells are at the root of cancer."
Dutch scientists carried out the controversial research to discover how easy it was to genetically mutate
H5N1 into a highly infectious "airborne" strain of human flu.
According to Sasisekharan, this knowledge could help scientists produce vaccines that do not include versions of the flu that can mutate
and so lead to "fitter" viruses.
a lot, but it can't mutate
to where it stops functioning...
Our study gives vital clues about what kinds of changes would be needed in order for them to mutate
and infect humans, potentially helping us to identify which viruses could lead to a pandemic."
Studies have suggested that pathogens called coxsackieviruses might be more likely to mutate
in hosts that are short on selenium, a metal involved in producing protective compounds called antioxidants.
The vaccine, manufactured by sanofi pasteur Inc., could be used in the event the virus mutates
and becomes capable of spreading through human-to-human contact, which could create a global pandemic.
Although the H5N1 avian flu is already a serious problem in Asia, it will not become a major threat to human health worldwide until and unless the virus mutates
into a strain that is both highly virulent and highly communicable from human to human.
Once GFAP mutates
, an abnormal protein is created, which, in turn, allows for a significant build-up of fibers around the myelin sheath, the insulation that protects the nerve fibers in the brain.