mutant frequency

mutant frequency

The ratio of mutated to non-mutated cells in a population. While mutant frequency is easier to measure than mutation rate, it may show large fluctuations depending on when the first mutation appeared in the population.
References in periodicals archive ?
The dose-response of mutant frequency was tested for significance with generalized linear modeling in R using a quasi-Poisson distribution (version 3.
At the low dose, brain showed a 7-fold increase in mutant frequency (p < 0.
Transgenic rodent assay for quantifying male germ cell mutant frequency.
Sublinear response in lacZ mutant frequency of Muta[TM]Mouse spermatogonial stem cells after low dose subchronic exposure to N-ethyl-N-nitrosourea.
Efficiency for unique identification of mutants in arrays from pool coordinates alone is theoretically achieved by choosing n and m on the basis of expected mutant frequency and empirically possible pooling ratio [11, 12].
The mutant frequency (Mt) in the cloning assay in 10 high-exposure workers was significantly higher (p < 0.
Our results at this point consistently indicate that exposure to BD at about 1-3 ppm is associated with an increase in HPRT mutant frequency.
In the case of the samples from the current study, significant increases in mutant frequency were measured using both the autoradiographic and cloning assays (35).
An analysis of in vivo mutant frequency in circulating T-lymphocytes in the normal human population: a comparison of four datasets.
The mutant frequency significatively increased during the fourth week after the exposure: 13.
The mutant frequency significantly increased 4 weeks after the intoxication: 13.
The improved assay showed a 2-fold increase of the mutant frequency with a 6-[micro]g/mL dose of crocidolite.