Five layers of the face (skin, subcutaneous tissue, musculoaponeurotic
layer, retaining ligaments and spaces, and periosteum and deep fascia) can be identified.
fibrosarcoma oncogene family A; FXR: farnesoid X receptor; GAPDH: glyceraldehyde-3-phosphate dehydrogenase.
We report a mutation of V-maf musculoaponeurotic
fibrosarcoma oncogene homolog B (MAFB), resulting in MCTO phenotypes.
One half of the mutations are associated with genes that code for crytallins, while a quarter with genes that encoded connexin and remaining to other genes that encrypted chromatin modifying protein-4B, beaded heat shock transcription factor-4, filament structural proteins-2, lens intrinsic membrane protein 2, avian musculoaponeurotic
fibrosarcoma, paired-like homeodomain transcription factor-3, Eph-receptor type-A2 and major intrinsic protein or aquaporin-0 (Hejtmancik, 2008; Huang and He, 2010).
A semicircular suborbicularis flap is designed at the lateral canthus and then extended laterally to the preauricular sulcus; it is elevated in a subcutaneous plane or sub-superficial musculoaponeurotic
system for additional blood supply.
It has seven highly conserved Nrf2-ECH homology domains, Neh1 toNeh7 [19,20].Neh1 domain includes a basic leucine zipper structure, which facilitates dimerization with small musculoaponeurotic
fibrosarcoma (sMaf) protein and binding to ARE .
fibrosarcoma bZIP transcription factor B (MAFB), a critical modulator of myeloid cell differentiation and proliferation [84, 85], enhances the expression of MSR1 in infiltrating myeloid cells.
Two transcription factors shown to be highly involved in the regulation of numerous antioxidant and detoxifying genes at transcriptional levels are Nrf2 [nuclear factor (erythroid-derived 2)-like 2] [3-5] and MAFG (v-Maf avian musculoaponeurotic
fibrosarcoma oncogene homolog G) .
Extended NLF is raised from the tip of NLF to the inferior border of mandible in the plane of the superficial musculoaponeurotic
system from both terminal points to the region of the central pedicle.
(35) v-MAF avian musculoaponeurotic
fibrosarcoma oncogene homolog gene regulates transcription of ADAMTS12 gene by binding to its "Maf recognition element" sequence.
It is at risk of iatrogenic injury overlying and anterior to massetter muscle where the nerve lies superficially underneath a thin layer of superficial musculoaponeurotic
Defects in NeuroD1 have been implicated in diabetes.(14) MafA (Beta cell nuclear MusculoAponeurotic
Fibrosarcoma oncogene family A) interacts with Pdx-1 and NeuroD1, and stimulates pancreatic B-cells to produce insulin--particularly when glucose levels are high.