muscleblind protein

muscleblind protein

product of the muscleblind (Mbnl) gene that participates in the organization of skeletal muscle Z bands and the epidermal attachments of Drosophila muscular systems; it has been implicated in the pathogenesis of myotonic dystrophy.
References in periodicals archive ?
When injected into the muscle cells of mice with myotonic dystrophy, the molecule found its way to the cell nucleus, broke up the deposits of toxic RNA, freed the captive muscleblind proteins, and ultimately improved the function of the muscle cells.
Myotonic dystrophy type 1 is associated with nuclear foci of mutant RNA, sequestration of muscleblind proteins and deregulated alternative splicing in neurons.