calpain-3(redirected from muscle-specific calcium-activated neutral protease 3)
calpain-3An intracellular, calcium-dependent, tissue-specific major cysteine protease encoded by CAPN3 on chromosome 15q15.1, the function of which is as yet not fully understood; it specifically binds to titin.
Abnormal calpain-3 mutations have been linked to limb-girdle muscular dystrophy type 2A (LGMD2A) [MIM:253600].
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