Toxicity of
muscimol and ibotenic acid containing mushrooms reported to a regional poison control center from 2002-2016.
Effects of linalool on [3h] mk801 and [3h]
muscimol binding in mouse cortical membrane.
[44.] Monda M, Amaro S, Sullo A, De Luca B (1995) Injection of
muscimol in the posterior hypothalamus reduces the PGE1-hyperthermia in the rat.
Improvement in tardive dyskinesia after
muscimol therapy.
The alkaloid includes sanguinarine,
muscimol, glycosin, ergotamine, ergobasine, mescaline, pilosine and nordihydrocapsaicin were identified from the potential extract and its fraction (Selvaraj et al.
and another active ingredient,
muscimol, but chose UV detection for
Methods: According to dose test, rats were randomly divided into control (Con), Ex,
muscimol (MUS, 0.1 mg/kg) and bicuculline (BIC, 0.5 mg/kg) groups, then all rats underwent once swimming Ex except ones in Con group only underwent training.
Control rats received infusions of
muscimol, a chemical that inactivates neurons in these brain regions, before receiving ketamine (Proc.
Sharif, "Modification by
muscimol of naloxone-precipitated withdrawal symptoms in morphine-dependent mice," General Pharmacology, vol.
Cardiovascular Responses to
Muscimol Microinjected into the VTA
The applications of non-classical bioisosterism have also been reported in a number of areas of pharmacology including adrenergic and anti adrenergic drugs [28, 30-31] , several NSAID classes like aryl acetic acid derivatives [32], cetroplac, tolmetin, indomethacin, etodolac [5], antibacterial drugs [33] , antidepressant of morpholine class [34] , neuropeptide substance P antagonists (NK1 antagonists) [35], cholinergic (muscarinic type) agonists [36], GABA modulators like
muscimol, thiomuscimol, isomuscimol as agonists [37-38], peptidomimetics [39], diuretics like ethacrinic acid [5] and 5-hyderoxy tryptamine (5-HT1A;1D) agonists like naratryptan and sumatryptan for acute attack of migraine [40].
In order to block MnPO pharmacologically,
muscimol (4 mM) was nanoinjected (100 nL) in experimental group (EXP).