muscarinic receptors

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Related to muscarinic receptors: cholinergic receptors

mus·ca·rin·ic re·cep·tors

membrane-bound proteins with an extracellular domain that contains a recognition site for acetylcholine (ACh); combination of Ach with the receptor initiates a physiologic change (slowing of heart rate, increased glandular secretory activity, and stimulation of smooth muscle contractions); changes are observed after treatment with the mushroom alkaloid muscarine. Muscarinic receptors are to be distinguished from nicotinic receptors.

muscarinic

pertaining to the transmission of nerve impulses mediated by muscarinic receptors; these may be adrenergic or cholinergic.

muscarinic activity

includes slowing and reduced stroke volume of the heart, bronchiolar constriction, arteriolar dilatation, increased tone, motility and secretion in the alimentary tract, and increases in salivation and lacrimation.

muscarinic blocking agents

block muscarinic receptors, e.g. atropine and the synthetic agents homatropine, methantheline, propantheline and methylatropine.

muscarinic receptors

cholinergic receptors of autonomic effector cells (and also on some autonomic ganglion cells and some central neurons) that are stimulated by muscarine and parasympathomimetic drugs and antagonized by atropine.

References in periodicals archive ?

Expression of muscarinic receptor subtypes in rat gastric smooth muscle: Effect of M3 selective antagonist on gastric motility and emptying.

Dipyrone in association with atropine inhibits the effect on gastric emptying induced by hypoglycemia in rats

2] and muscarinic receptors inducing the release of endothelial NO and prostaglandins.

Involvement of bradykinin [B.sub.2] and muscarinic receptors in the prolonged diuretic and antihypertensive properties of Echinodorus grandiflorus (Cham. & Schltdl.) Micheli

2] muscarinic receptors activity on motor nerve terminal, i.

Atropine is more efficient than ZM241385 to reduce a drastic level of fade caused by cisatracurium at 50 Hz/Atropina e mais eficiente que ZM241385 para reduzir o intenso nivel de fadiga causada por cisatracurium a 50 Hz

NG-nitro L-arginine methyl ester and other alkyl esters of arginine are muscarinic receptor antagonists.

Role of NO in arterial vascular function of intertidal fish (Girella laevifrons) and marine fish (Isacia conceptionis)/Papel do NO na funcao vascular arterial de peixes entremares (Girella laevifrons) e peixes marinhos (Isacia conceptionis)

Muscarinic receptors were determined by binding assays using a single concentration (Kd) of the specific tritiated ligand antagonist [sup.

Mercury vapour long-lasting exposure: lymphocyte muscarinic receptors as neurochemical markers of accidental intoxication

Antispasmodic and bronchodilator activities of Artemisia vulgaris are mediated through dual blockade of muscarinic receptors and calcium influx.

Short communication - URINARY BLADDER RELAXANT EFFECT OF ARTEMISIA VULGARIS AND ASPALATHUS LINEARIS

Regulation of rat mesencephalic GABAergic neurones through muscarinic receptors.

Evaluation of GABA receptors of ventral tegmental area in cardiovascular responses in rat

There are five subtypes of muscarinic receptors expressed in the bladder.

The paediatric neuropathic bladder

These results indicate that the activation of SERCA and muscarinic receptors may play an important role in the effect of DECC on the cardiac contractility, heart rate and coronary flow.

The effects and mechanisms of action of diethylcarbamazine citrate in isolated rat hearts/dietilkarbamazin sitrat'in izole sican kalplerindeki etkileri ve etki mekanizmalari

Activation of muscarinic receptors inhibits apoptosis in PC12M1 cells.

Activation of Ml mAChRs by lesatropane rescues glutamate neurotoxicity in PC12 cells via PKC-mediated phosphorylation of ERK1/2

The concept of muscarinic receptors originated from a report by Dale in 1914, (1) although he did not use the term receptor.

Molecular properties of muscarinic acetylcholine receptors

When bound to the muscarinic receptors, Ach is suppressed, allowing for sympathetic nervous system symptoms ("fight or flight") to activate.