muscarinic


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mus·ca·rin·ic

(mŭs'kă-rin'ik),
1. Having a muscarinelike action, that is, producing effects that resemble postganglionic parasympathetic stimulation.
See also: muscarine, nicotinic.
2. An agent that stimulates the postganglionic parasympathetic receptor.
See also: muscarine, nicotinic.

mus·ca·rin·ic

(mŭs'kă-rin'ik)
1. Having a muscarinelike action, i.e., producing effects that resemble postganglionic parasympathetic stimulation.
2. An agent that stimulates the postganglionic parasympathetic receptor.
See also: muscarine, nicotinic

muscarinic

1. Producing the effects of post-ganglionic cholinergic stimulation of the parasympathetic. Having an effect similar to that of the mushroom poison MUSCARINE.
2. Of an acetylcholine receptor that responds to muscarine. Compare NICOTINIC.

muscarinic

(in physiological terminology) having acetylcholine receptors that are sensitive to muscarine but not to nicotine.
References in periodicals archive ?
On the other hand muscarinic [M.sub.2] and [M.sub.4] receptors preferentially couple to G[alpha]i/o subunit that inhibits adenylate cyclase and reduce the production of second messenger cyclic adenosine monophosphate (cAMP).
Triple Inhaled Therapy: Long-Acting Muscarinic Antagonist + Long-Acting Beta[sub]2-Adrenoceptor Agonist + Inhaled Corticosteroids
The signs of OPP may be classified as effects secondary to nicotinic, muscarinic, and CNS receptor overstimulation.6 Clinical presentation depends on the specific agent involved, the type of exposure and the quantity absorbed5.
Heterogeneity of presynaptic muscarinic receptors involved in modulation of transmitter release.
With all, our objective was to evaluate the role of the acetylcholine-COX pathway by blockade with muscarinic antagonist (Atropine) and blockade with an unspecific inhibitor of cyclooxygenases (Indomethacin) in the arterial vessel of dorsal, mesenteric, pulmonary and iliac arteries in C.
and Markee and Hunter [2, 3] analysed the effects of blocking the muscarinic system with atropine sulfate, revealing that the cholinergic system plays a role in regulating the secretion of ovulating hormones in rats and rabbits.
Patients exhibit muscarinic and nicotinic symptoms depending upon severity of compounds.
The signs of acute OP poisoning may be classified as effects secondary to muscarinic, nicotinic, and central nervous system receptor overstimulation.
However, it has been shown that the values of [TOF.sub.fade] and Fade obtained in the presence of antinicotinic agents may express different conditions of neuromuscular transmission, as different patterns of stimulation applied on motor nerve in the absence or in the presence of drugs, may modify the autoregulatory cholinergic (facilitatory-nicotinic receptors expressing [alpha]3[beta]2 subunits, facilitatory-[M.sub.1] and inhibitory-[M.sub.2] subtypes of muscarinic receptors) and the modulatory (facilitatory-[A.sub.2A] and inhibitory-[A.sub.1] adenosine receptors) mechanisms on the terminal (Bornia, Bando, Machinsky, Pereira, & Prado, 2009; Bornia, Sa, & Prado, 2011; Pereira, Bornia, Sa, & Prado, 2011).
The aim of this study was to prove the in vivo efficacy of Gegen on improving detrusor overactivity and its possible synergism with darifenacin (a first-line muscarinic receptor-3 inhibitor) in spontaneously hypertensive rats (SHR), a rat model exhibiting symptoms of detrusor overactivity.
(3-9) Scopolamine blocks central muscarinic cholinergic receptors, which reduces production of glutamate receptors and leads to reduced glutamate transmission and neurotoxicity.
In November 2014, Townsend Letter ran my article which theorized that in a subgroup of CFS patients, autoantibodies to beta adrenergic receptors (BAR) and/ or muscarinic cholinergic receptors (MCR) may play a role.