murine leukemia

mu·rine leu·ke·mi·a

a leukemic disorder of mice caused by a number of different type C retroviruses.
References in periodicals archive ?
Translocation t (9;22) leads to fusion of breakpoint cluster region (BCR) gene on chromosome 22 and Abelson murine leukemia (ABL1) gene located on chromosome 92.
PIM kinases named for the genomic site, Proviral Integration site of Moloney Murine leukemia virus.
(12) This might be partially explained by the ability of NRAS to activate both v-raf-1 murine leukemia viral oncogene homolog 1 (CRAF) and the PI3K signaling pathway.
The BM aspirate collected 2 months after the allo-HSCT showed increased AML blasts (10.00%) and Wilms' tumor 1 ( WT1 )/Abelson murine leukemia viral oncogene homolog ( ABL ) transcript (0.03%).
BLV, bovine leukemia virus; LTR, long terminal repeat (promoter region); gag, group-specific antigen (capsid region); pol, polymerase (reverse transcription); env, envelope; tax, trans-activating region of the X gene; RSV, Rous sarcoma virus; MSV, murine sarcoma virus; MMTV, mouse mammary tumor virus; MPMV, Mason- Pfizer monkey virus; MuLV, murine leukemia virus; FeLV, feline leukemia virus; FLK, fetal lamb kidney; STLV, simian T-cell leukemia virus; HTLV, human T-cell leukemia virus; HPV, human papillomavirus; EBV, Epstein-Barr virus; HERV, human endogenous retrovirus.
Most commonly, the RT used here is the Moloney murine leukemia virus RT (M-MLV RT); in addition to its pure RT activities, it has other enzymatic functions which the technique will make use of.
In 2009, (http://www.sciencemag.org/content/326/5952/585) a paper published in the journal Science linked the disease to a mouse retrovirus called xenotropic murine leukemia virus-related virus, or XMRV, after finding traces of it in 68 chronic fatigue syndrome patients out of a 101-patient sample.
(8.) Zhao M, Kiyoi H, Yamamoto Y, Ito M, Towatari M, Omura S, Kitamura T, Ueda R, Saito H, Naoe T: In vivo treatment of mutant FLT3-transformed murine leukemia with a tyrosine kinase inhibitor.
Human colon adenocarcinoma cell line (colo 205), human hepatoma cell line (Hep G2), human murine leukemia cell line (WEHI-3), mouse melanoma cell line (B16-F1), human melanoma cell line (A375 S2) and promyelomonocytic cells line (HL-60) were obtained from the Food Industry Research and Development Institute (Shinchu, Taiwan).
The nation's public health is at stake as scientists report that 7% of samples taken from the blood supply in The United States shows positive for a family of murine leukemia viruses.

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