multiple endocrine neoplasia type 2


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multiple endocrine neoplasia type 2

(1) MEN 2A (multiple endocrine neoplasia type 2A).
(2) Multiple endocrine neoplasia type 2B (type 3).
References in periodicals archive ?
RET proto-oncogene genetic screening of families with multiple endocrine neoplasia type 2 optimizes diagnostic and clinical management in China.
Preoperative clinical data of patients (*) Sporadic MEN2A MTC Age (Mean, years) 47.6[+ or -]1.05 35.6[+ or -]2.78 Stage at diagnosis Stage I 41 6 Stage II 7 2 Stage III 17 4 Stage IV 26 1 CT (mean, pg/mL) 1072[+ or -]1102 704[+ or -]594 FMTC p Age (Mean, years) 41.3[+ or -]2.9 p<0.01 Stage at diagnosis Stage I 8 NS Stage II 0 NS Stage III 3 NS Stage IV 2 p<0.01 CT (mean, pg/mL) 254[+ or -]569 p<0.05 MTC: Medullary thyroid carcinoma, CT: calcitonin, FMTC: familial medullary thyroid carcinoma, MEN2A: multiple endocrine neoplasia type 2 A, NS: non significant (*) Tumor stage at the time of diagnosis was available for 117 patients Table 5.
Very early detection of RET protooncogene mutation is crucial for preventive thyroidectomy in multiple endocrine neoplasia type 2 children: presence of C-cell malignant disease in asymptomatic carriers.
Pheochromocytoma in von Hippel-Lindau disease: distinct histopathologic phenotype compared to pheochromocytoma in multiple endocrine neoplasia type 2. Endocr Pathol.
RET oligonucleotide microarray for the detection of RET mutations in multiple endocrine neoplasia type 2 syndromes.
Denaturing gradient gel electrophoresis to diagnose multiple endocrine neoplasia type 2. Clin Chem 1996;42:598-603.
Mutations of the RET proto-oncogene in the multiple endocrine neoplasia type 2 syndromes, related sporadic tumours, and Hirschsprung disease.
Until then, the genes responsible for inheritable forms of paragangliomas were restricted to those underlying the syndromic forms of the disease; RET gene in multiple endocrine neoplasia type 2, VHL in von Hippel-Lindau disease; and NF1 in neurofibromatosis type 1.
Schuffenecker et al., "The relationship between specific ret proto-oncogene mutations and disease phenotype in multiple endocrine neoplasia type 2: international RET mutation consortium analysis," Journal of the American Medical Association, vol.
Sobrinho, "Molecular diagnosis of multiple endocrine neoplasia Type 2," Expert Review of Molecular Diagnostics, vol.
Raue et al., "Pheochromocytoma in multiple endocrine neoplasia type 2: European study," Journal of Internal Medicine, vol.
Multiple endocrine neoplasia type 2 and RET: from neoplasia to neurogenesis.

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