Hendriks, "Histologic multifocality
of Tis, T1-2 breast carcinomas: implications for clinical trials of breast-conserving surgery," Cancer, vol.
Ferracin et al., "MicroRNA-221 targets Bmf in hepatocellular carcinoma and correlates with tumor multifocality
," Clinical Cancer Research, vol.
(10,12) The occurrence of multiple IMFTs--a rare phenomenon--is purported to be a function of multifocality
rather than metastatic spread.
The average tumor size, incidence of multifocality
, and incidence of high-grade tumor were significantly less in women who had undergone mammography at or within a year prior to diagnosis than in the women whose last mammogram was more than a year prior to diagnosis and women who had never had a mammogram (17.8 mm, 24 mm, and 29 mm; 12%, 22%, and 36%; and 31%, 32%, and 46%, respectively).
is not related to malignancy, and is often associated with neurofibromatosis type 2.171 Only four malignant penile schwannomas have been described in the literature (three of them were associated with Von Recklinghausen disease), and none of the benign tumors were associated with this disease.
(b) High-risk women who have already developed breast cancer: since these patients have a disproportionately high rate of multifocality
and multicentricity .
Tumor diameter, multifocality
, lymph node involvement, Hashimoto's thyroiditis, follicular variant of papillary carcinoma, extrathyroidal extension, and vascular or capsular invasion were assessed histopathologically.
They frequently present in childhood and young adulthood; always arise in the stomach; tend to multifocality
, predominantly epithelioid morphology, and absence of KIT and PDGFRA mutations; and frequently metastasize to lymph nodes but tend to indolent behavior.
Furthermore, in a MRI study, the authors showed that tumors with high TIL levels tend to represent round shape, circumscribe margin, homogenous enhancement and lack of multifocality
These patients should be educated to expect bilateral multifocality
. When all the credential are analysed into every patients the incidence of unhappy patients will be minimized considerably.
was detected in 8.6%, 4%, and 0% of Groups 1, 2, and 3, respectively (p<0.05 for both Group 1 vs.
Model 2, adjusted for sex, age, TSH before surgery, tumor size, extrathyroidal extension, multifocality
, nodular goiter, and Hashimoto thyroiditis.