The concentration of soluble protein in the multienzyme
of stomach and intestine extracts was determined with the technique described by Bradford (1976).
"based on these results, one is led to consider a simple metabolic deficiency model for AD; amyloid I-42 blockade of the PDH multienzyme
complex is the source of amyloid toxicity and leads to loss of bioenergetic potential and neurotransmitter production, which ultimately leads to neuronal death.
It allows the assessment of mitochondrial function in an integrated cellular system, in a physiological environment: normal intracellular position and assembly, preserved interactions with cytoskeleton, nucleus and endoplasmic reticulum, intact multienzyme
system of intracellular energy transfer.
Regarding recommendations for nutritional treatment, the Canadian Consensus (21) proposes that patients should be encouraged to eat balanced and nutritious meals at regular times, maintain good hydration, take multienzyme
along with meals when associated with irritable bowel syndrome (IBS), use supplements when needed for treatment.
Further, nanoceria has also been shown to have multienzyme
mimetic activities such as superoxide dismutase, superoxide oxidase, catalase and oxidase and because of this property, nanoceria are capable of regenerating their antioxidant activity [11,14-16].
[15.] WaeonukulR, KyuKL, SakkaK, Ratanakhanokchai K, Isolation and characterization of a multienzyme
complex (cellulosome) of the Paenibacillus curdlanolyticus B-6 grown on Avicel under aerobic conditions.
Delcroix M, Sajid M, CaVrey CR, Lim K-C, Dvorak J, Hsieh I, Bahgat M, Dissous C, McKerrow JH (2006) A multienzyme
network functions in intestinal protein digestion by a platyhelminth parasite.
In theory, sum of FCCs in a linear system is 1 [5, 40, 42-44, 89, 90], but the value of it can increase if the system includes enzyme-enzyme interactions, direct channeling, and/or recycling within multienzyme
complexes (i.e., system becomes nonlinear) [79, 80, 91, 92].
Gingeras, "Isothermal, in vitro amplification of nucleic acids by a multienzyme
reaction modeled after retroviral replication," Proceedings of the National Academy of Sciences of the United States of America, vol.
One of the heterodisulfide molecules is reduced bya multienzyme
complex consisting of a [NiFe] hydrogenase (Mvh) and a heterodisulfide reductase (HdrABC), which uses [H.sub.2] as electron donor and transfers electrons to heterodisulfide and ferredoxin (Fd) in a bifurcation reaction.
Cathepsin A (CathA) is a ubiquitously expressed component of a lysosomal multienzyme
complex (LMC) with independent protective and catalytic functions [1, 2].
Hydrolysis of BSA and actin is carried out by a multienzyme