multicentric


Also found in: Dictionary.

multicentric

Medspeak
adjective Referring to that which occurs in many sites in the body, as in a multicentric malignancy; in general, multifocal is preferred.

Trial
adjective Referring to that which occurs in multiple medical centres or hospitals, as in a multicentric study; in general, multicentre is preferred.
References in periodicals archive ?
Papillary carcinoma can be unifocal, multifocal or multicentric. In present study single nodular lesions were identified in 12 cases (27.2%), more than one lesion in the same lobe (multifocal) in 11 cases (25%) and focal lesions in both lobes (multicentric) in 7 cases (15.9%).
This virus is also held responsible for the development of primary effusion lymphoma and multicentric Castleman disease.
Middleton et al (15) observed identical ER/PR/HER2 staining pattern in 14 of 32 multicentric cases (44%), in which additional tumor foci were also tested for biomarkers.
Four subtypes of CD are described: (1) hyaline vascular--usually unicentric, (2) plasma cell rich--more frequently multicentric (3) HHV-8 associated CD--mainly multicentric in the immunocompromised and (4) multicentric not otherwise specified [3].
Since more cats are being tested and isolated if positive or vaccinated if negative, the incidence of mediastinal and multicentric lymphomas in cats has decreased, but intestinal lymphomas have picked up.
Multifocal hepatocellular carcinoma: Intrahepatic metastasis or multicentric carcinogenesis?
Six years of R&D with 12 $millions invested, including the last largest clinical multicentric trial never ever made, NEWROFEED-Koala, successfuly lead to the grant of a CE mark class IIa in Europe.
It has been reported that multicentric smooth muscle tumors arising from vaginal wall and cervix can be invasive and may result in considerable haemorrhages and death in goats (Cooper and Valentine, 2002; Uzal and Puscher, 2008).
Kaposi's sarcoma and multicentric Castleman's disease VHH-8 positive--HIV negative: An etiological subgroup
Multicentric carpotarsal osteolysis syndrome (MCTO, OMIM # 166300), also called idiopathic multicentric osteolysis with progressive nephropathy, is a rare autosomal dominant disorder characterized by progressive osteolysis, predominantly of the carpal and tarsal bones.
CD can be unicentric (U-CD), usually restricted to the mediastinum, or multicentric (M-CD): the first is typically identified incidentally or though symptoms from the local mass effect; the latter form is more symptomatic, including fever, night sweats, weight loss, and anorexia.
It can be unicentric or multicentric. HHV8 related clinical manifestations range from Kaposi Sarcoma (KS), intracavity primary effusion lymphoma (PEL) and systemic multicentric Castleman disease (MCD).

Full browser ?