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A gene (DSS-AHC critical region on the X chromosome, gene 1—formally known, per HUGO nomenclature, as NR0B1) located on chromosome Xp21.3 that encodes a protein containing a DNA-binding domain, which acts as a dominant-negative regulator of transcription mediated by the retinoic acid receptor. DAX1 also acts as an anti-testis gene by antagonising SRY.

Molecular pathology
DAX1 mutations cause both X-linked congenital adrenal hypoplasia and hypogonadotropic hypogonadism.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.


Abbrev. for Department of Social Security.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005
References in periodicals archive ?
With Multi-Sim, customers can share their data and minutes across multiple devices, said du in a statement.
With Multi-SIM, all customers need to do is assign one primary SIM to their main device, with up to four secondary SIMs in other devices, the telecom operator said.
Despite the lower profit, the company remained optimistic, saying "the mobile business thrived against the challenges posted by competition, notwithstanding peaking penetration levels driven in part by multi-SIM usage and subscribers' preference for services offering the best value for their money."
However, Nokia, a late entrant in the multi-SIM device category, fast tracked the process of consolidation by rolling out five models by Sept 2011, to make its presence felt in every price segment in India.
At first, the Acision Cloud Service Store will offer personalised messaging services including group messaging, auto-reply and auto-signature, message copy, personalised black/white list, distribution list, multi-SIM, alias and divert.
The firm predicts that the multi-SIM phenomenon, "attractive" on-net offers from all three major mobile phone providers, a drop in mobile handsets all coupled with lower subscription fees will be the driving factors behind saturation.
However, recent operator comments suggests that 50% of these connections are inactive and as much 70% of the connections added in 2009 were multi-SIM users.
Operators in emerging markets today deal with major challenges related to declining growth, ARPU pressure (due to multi-SIM behaviour) and rotational churn.
Multi-sim phones, with up to 10 SIM cards active on one account, have been introduced by Vodafone.
- Mobile: mobile penetration rates will increase in most countries, and will only decline in Cambodia and Malaysia due to a fall in multi-SIM ownership

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