mule


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Related to mule: Drug mule

body packer

a person who transports illicit drugs by concealment in body cavities.

mule

(myo͞ol)
n.
1. The sterile hybrid offspring of a male donkey and a female horse, characterized by long ears and a short mane.
2. A sterile hybrid, as between a canary and other birds or between certain plants.

HUWE1

A gene on chromosome Xp11.22 that encodes E3 ubiquitin-protein ligase, which mediates ubiquitination and proteasomal degradation of target proteins. HUWE1 regulates apoptosis by catalysing the polyubiquitination and degradation of MCL1. It also plays a role in base-excision repair and in regulating neural differentiation and proliferation by polyubiquitination and degradation of MYCN. It may also regulate concentration of CDC6 after DNA damage by targeting it for degradation.

Molecular pathology
Defects in HUWE1 cause mental retardation, X-linked, syndromic Turner type (MXRST) and mental retardation, X-linked, type 17/31.

mule

Drug slang A street term for a carrier of illicit drugs. See Body packer syndrome.
References in classic literature ?
"I'm the breech-piece mule of number two gun of the First Screw Battery," said the mule, "and the other's one of your friends.
"Oh, beg your pardon," said the mule. "It's too dark to see much.
He at once called to Sancho, who, however, had no mind to come, as he was just then engaged in unloading a sumpter mule, well laden with provender, which these worthy gentlemen had brought with them.
Looks easy, doesn't it?--one minute, the sixtieth part of an hour, to be precise, sixty seconds, to stick on the back of an affectionate josher mule like Barney.
she is an old steady mare, with a little bell round her neck; and wherever she goes, the mules, like good children, follow her.
"Sir monk," said De Guiche, "confess well that brave man; and be not concerned for your expenses or for those of your mule; all is paid."
I can send you by boat as far as the river travel is good, and then have mules and ox-carts in waiting."
Darkness, outstripping some visitors on mules, had risen thus to the rough convent walls, when those travellers were yet climbing the mountain.
Now at last, however, he is safely in paradise, and so I may jog on upon my earthly way." He mounted, as he spoke, a white mule which had been grazing by the wayside, all gay with fustian of gold and silver bells, and rode onward with Sir Nigel's party.
``Something more potent than that,'' answered the Jester; ``for when would repentance or prayer make Gurth do a courtesy, or fasting or vigil persuade him to lend you a mule? l trow you might as well have told his favourite black boar of thy vigils and penance, and wouldst have gotten as civil an answer.''
Before him went the mules drawing the four-wheeled waggon, and driven by wise Idaeus; behind these were the horses, which the old man lashed with his whip and drove swiftly through the city, while his friends followed after, wailing and lamenting for him as though he were on his road to death.
On this he gave his orders to the servants, who got the waggon out, harnessed the mules, and put them to, while the girl brought the clothes down from the linen room and placed them on the waggon.