mucopolysaccharide


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mucopolysaccharide

 [mu″ko-pol″ĭ-sak´ah-rīd]
a group of polysaccharides that contain hexosamine, that may or may not be combined with protein and that, dispersed in water, form many of the mucins.

mu·co·pol·y·sac·cha·ride

(myū'kō-pol'ē-sak'ă-rīd),
General term for a protein-polysaccharide complex obtained from proteoglycans and containing as much as 95% polysaccharide; mucopolysaccharides include the blood group substances. A more modern term is glycosaminoglycan, because all of the known six classes contain major amounts of d-glucosamine and d-galactosamine.

mucopolysaccharide

/mu·co·poly·sac·cha·ride/ (-sak´ah-rīd)
2. any polysaccharide with high hexosamine content, including the glycosaminoglycans and also neutral polysaccharides such as chitin.

mucopolysaccharide

(myo͞o′kō-pŏl′ē-săk′ə-rīd′)

mucopolysaccharide

[myo̅o̅′kōpol′ēsak′ərīd]
Etymology: L, mucus + Gk, polys, many, sakcharon, sugar
a polysaccharide containing hexosamine and sometimes occurring with protein, such as mucins.

mu·co·pol·y·sac·cha·ride

(myū'kō-pol'ē-sak'ă-rīd)
General term for a protein-polysaccharide complex obtained from proteoglycans and containing as much as 95% polysaccharide; mucopolysaccharides include the blood group substances. A more current term is glycosaminoglycan.

mucopolysaccharide

POLYSACCHARIDEs containing amino sugars or that are polymers of MONOSACCHARIDES in which one of the -OH groups is replaced by an NH2 group. Mucopolysaccharides are important structural materials in the body forming the ground substance of many connective tissues in which fibrous proteins are embedded. Now more commonly called glycosaminoglycans.

mucopolysaccharide

any polysaccharide, such as hyaluronic acid or heparin, that contains either an amino sugar or a derivative. Also called glycosaminoglycans (GAGs). Often GAGs are found covalently bound to core proteins forming proteoglycans.

Mucopolysaccharide

A complex molecule made of smaller sugar molecules strung together to form a chain. Found in mucous secretions and intercellular spaces.
Mentioned in: Mucopolysaccharidoses

mucopolysaccharide

protein-polysaccharide complex

mu·co·pol·y·sac·cha·ride

(myū'kō-pol'ē-sak'ă-rīd)
General term for a protein-polysaccharide complex obtained from proteoglycans and containing as much as 95% polysaccharide.

mucopolysaccharide

a group of polysaccharides that contain hexosamine, which may or may not be combined with protein; when dispersed in water, mucopolysaccharides form many of the mucins.

acid mucopolysaccharide
the amorphous, PAS-positive intercellular substance of most connective tissue. Formed by fibroblasts and osteoblasts.

Patient discussion about mucopolysaccharide

Q. Does GAG really help? My mother suffers from osteoarthritis, and after taking a lot of pain-killers someone offered us to try glycosaminoglycans. Does it really help? It’s quite expensive….

A. As far as I know it wasn’t proved in well-controlled trials to benefit the patients over placebo, so if it’s a consideration for you, I’m not sure it justifies the price. However, I’m only a lay-man, so consulting a professional (i.e. a doctor) is better.

More discussions about mucopolysaccharide
References in periodicals archive ?
The ABPAS stains neutral mucins and fungal walls bright red or magenta, and acid mucopolysaccharides blue.
40], the presence of oxidant (AAPH) induces an increase in the mucopolysaccharides secretion located at microvilli glycocalyx.
The epithelium comprised large quantities of mucous glands which were prepared in a homogeneous way throughout its whole surface, with positive response to the combination periodic acid-Schiff (PAS) and Alcian Blue (B), indicating neutral and acidic mucopolysaccharides, respectively (Figure 2A).
Investigations include urine spot tests which are readily available to screen for mucopolysaccharides but are associated with false-positive and false-negative results.
The persistent symbiosis leads to reparative connective tissue macromolecular deposition of acidic mucopolysaccharides, glycoproteins, collagen and elastin leading to fibrotic changes in the heart, vessel wall, thyroid and pancreas contributing to EMF, CCP, MNG and mucoid angiopathy [4,32].
16) Fujita et al (18) looked at the effect of glucosamine, active absorbable algal calcium, porcine skin collage, composite mucopolysaccharide, and vitamin C on back or knee pain.
Dietary carotenoid pigment supplementation influences hepatic lipid and mucopolysaccharide levels in rainbow trout (Oncorhynchusmykiss), Comparative Biochemistry and Physiology.
Cardiovascular changes in MPS Echocardiographic abnormalities in the mucopolysaccharide storage diseases.
15) It is then plausible that, in birds, formation of uric acid cloacoliths is predisposed by an alteration of the solubility and chemistry of the uric acid mucopolysaccharide microspheres, which could lead to uric acid precipitation and aggregation in a physiologically supersaturated environment.
Louis School recently had a Dress for MPS Day to call attention to efforts to find a cure for mucopolysaccharide disorder, which affects the body's metabolism.
Special staining techniques were used to demonstrate collagen fibres (Masson's trichrome), reticular fibres (Silver staining), elastic fibres (Verhoeff's staining) and mucopolysaccharide (Periodic Acid Schift--Alcian blue, PAS-AB) as per Luna [12].
The appearance of the epidermis may be improved and there may be some increase in dermal collagen and mucopolysaccharide synthesis.