Mathee K, Ciofu O, Sternberg C, Lindum PW, Campbell JI, Jensen P, Johnsen AH, Givskov M, Ohman DE, Molin S, Hoiby N, Kharazmi A Mucoid
conversion of Pseudomonas aeruginosa by hydrogen peroxide: a mechanism for virulence activation in the cystic fibrosis lung.
PAOmucA22 carries a mutation in the mucA gene that encodes the anti-sigma factor MucA, resulting in a constitutive mucoid
phenotype (Mathee et al.
Production of alginate by the strain was identified as either M (mucoid
) or NM (non-mucoid) For example, P1AM means that a mucus producing strain (mucoid
) (A) was isolated from patient 1, while P1AMN is a mucus not producing strains (nonmucoid) that was also isolated from patient 1.
Most isolates are mucoid
, and most are oxidase-positive, leading to a possible misidentification of Pseudomonas aeruginosa mucoid
This is a 22 years female, non-smoker of nonconsanguineous parents presented to OP clinic in (March 2017) with chief complaints of cough with yellowish mucoid
sputum for the previous one month with recurrent cold associated with progressive increase in shortness of breath since three years.
Our patient had an infection with a mucoid
Kp strain sensitive to all antibiotics except ampicillin suggesting a hypervirulent strain.
Since the blood agar plate had shiny mucoid
, cream, circular colonies so string test was done that was positive with a string length of more than 5mm (Figure).
Cryptococcus is a spherical to oval, thin walled budding yeast enveloped in a thick mucoid
The formation of mucoid
or viscous growth on sucrose agar was taken as positive for EPS production (Garvie, 1984).
Clinical signs were sneezing, coughing, and mucoid
nasal and ocular discharge.
Microscopic examination of the right ear revealed a bulging but intact tympanic membrane, with mucoid
fluid filling the middle ear space (figure).
The eye discharge in conjunctivitis may be clear (serous), mucuslike (mucoid
), or puslike (purulent).