O'Riordan, "
Mucociliary clearance in the airways," American Journal of Respiratory and Critical Care Medicine, vol.
Another clinical comparison between dexpanthenol seawater spray (Mar plus) and normal saline irrigation resulted in less crusting at the 2nd check-up visit and better
mucociliary clearance at the 4th check-up in the intervention group [79].
To our knowledge, this is the first study to associate changes in airway
mucociliary clearance with changes in exhaled [NO.sub.x] in human subjects.
The effect of saline solutions on nasal patency and
mucociliary clearance in rhinosinusitis patients.
But other severe pulmonary infections like pertussis or measles pneumonia can also damage the
mucociliary clearance mechanism and trigger the bronchiectatic process.
Besides facilitating bacterial adherence to epithelial cells, cigarette smoke decreases
mucociliary clearance by the respiratory epithelium and induces inflammation that may cause epithelial injury, predisposing to colonization, he said (Clin.
Medical treatment of
mucociliary clearance by pharmacological increase of CBF could be a basic therapeutic approach by eliminating the congestion of mucus secretion.
Second, pulmonary
mucociliary clearance mechanisms are minimal in the alveolar region of the lungs.
As the patient's condition deteriorated progressively and he had difficulty in expectorating sputum, salbutamol, 0.5 g four times a day, driven by a jet nebulizer at 6 L of oxygen per ruin, was given to assist
mucociliary clearance. His oxygen saturation remained normal without supplemental oxygen.
Normal airway clearance is accomplished by two major mechanisms: the
mucociliary clearance system (MCS) and the ability to cough.
Airway clearance problems may be due to problems with loss of cough reflex, slowing of
mucociliary clearance, and alterations in airway mediation, all due to the denervation.
Mechanical disruption of ciliated airways (eg, bronchoscopic examination, endotracheal intubation or prolonged coughing) causes mucociliary dysfunction.[32] Opiates, benzodiazepines and general anesthetics inhibit
mucociliary clearance of the airways.[3]
