7] Decreased tracheobronchial mucociliary
clearance is higher in patients with pSS compared to normal.
He focused on removing key areas of obstruction to allow normal mucociliary
clearance represents a host defense mechanism of airways that can be compromised by various pathologic conditions, such as nasal septal deviation.
clearance), and impaired activity of one branch of the immune system (i.
Mucosal secretion and air conditioning are primary functions of sinuses which is maintained properly by the mucociliary
clearance of cilia present in the sinus.
This lacks the mucociliary
defences of the rest of the respiratory tract, so relies on phagocytosis by alveolar macrophages.
Small particulate matter can travel to the alveolar level of the respiratory system which lacks the mucociliary
defences of the rest of the respiratory tract, therefore relying upon phagocytosis by alveolar macrophages.
Smoking destroys the ciliated cell of nasal mucosa and reduces secondary clearance of mucociliary
action that can lead to AR.
The main epithelial defence mechanism in the lung is airway mucociliary
clearance [96, 97], whereas in the distal, alveolar regions of the lungs, primary defence against potential pathogens is maintained by alveolar macrophages.
Symptoms occur due to ineffective cough secondary to pathologic dilation in the tracheobronchial tree and the impairment of mucociliary
activity leading to difficulty in expectorating secretions and resultant recurrent respiratory infections.
sup] Like other respiratory epitheliums, adenoidal epithelium may serve as the central part of the upper airway innate immunity related to mucociliary
clearance, [sup] secretion of endogenous antimicrobial peptides (AMPs), [sup] interacting with the adaptive immune response, and expressing pattern recognition receptors (PRRs) to identify pathogen-associated molecular patterns (PAMPs).
Accordingly, the current study aimed to explore the efficacy of EPs[R] 7630 in an infective bronchitis animal model, and on common symptoms associated with airways infection, cough and mucociliary