mucinous carcinoma

Also found in: Dictionary, Thesaurus, Encyclopedia.
Related to mucinous carcinoma: mucinous cystadenoma


 [kahr″sĭ-no´mah] (pl. carcinomas, carcino´mata)
a malignant new growth made up of epithelial cells tending to infiltrate surrounding tissues and to give rise to metastases. A form of cancer, carcinoma makes up the majority of the cases of malignancy of the breast, uterus, intestinal tract, skin, and tongue.
adenocystic carcinoma (adenoid cystic carcinoma) carcinoma marked by cylinders or bands of hyaline or mucinous stroma separated or surrounded by nests or cords of small epithelial cells, occurring in the mammary and salivary glands, and mucous glands of the respiratory tract. Called also cylindroma.
alveolar carcinoma bronchioloalveolar carcinoma.
basal cell carcinoma the most common form of skin cancer, consisting of an epithelial tumor of the skin originating from neoplastic differentiation of basal cells, rarely metastatic but locally invasive and aggressive. It usually occurs as small pearly nodules or plaques on the face of an older adult, particularly on a sun-exposed area of someone with fair skin. It has been divided into numerous subtypes on the basis of clinical and histological characteristics.
basosquamous carcinoma carcinoma that histologically exhibits both basal and squamous elements.
bronchioalveolar carcinoma (bronchiolar carcinoma) (bronchioloalveolar carcinoma) (bronchoalveolar carcinoma) a variant type of adenocarcinoma of the lung, with columnar to cuboidal epithelial cells lining the alveolar septa and projecting into alveolar spaces in branching papillary formations. Called also alveolar carcinoma or adenocarcinoma and bronchiolar, bronchioloalveolar, or bronchoalveolar adenocarcinoma.
bronchogenic carcinoma any of a large group of carcinomas of the lung, so called because they arise from the epithelium of the bronchial tree. Four primary subtypes are distinguished: adenocarcinoma of the lung, large cell carcinoma, small cell carcinoma, and squamous cell carcinoma.
cholangiocellular carcinoma a rare type of hepatocellular carcinoma arising from the cholangioles, consisting of two layers of cells surrounding a minute lumen. Called also bile duct carcinoma and cholangiocarcinoma.
chorionic carcinoma choriocarcinoma.
colloid carcinoma mucinous carcinoma.
cylindrical cell carcinoma carcinoma in which the cells are cylindrical or nearly so.
embryonal carcinoma a highly malignant germ cell tumor that is a primitive form of carcinoma, probably of primitive embryonal cell derivation; it usually arises in a gonad and may be found either in pure form or as part of a mixed germ cell tumor.
epidermoid carcinoma squamous cell carcinoma.
giant cell carcinoma a poorly differentiated, highly malignant, epithelial neoplasm containing many large multinucleated tumor cells, such as occurs in the lungs.
hepatocellular carcinoma primary carcinoma of the liver cells with hepatomegaly, jaundice, hemoperitoneum, and other symptoms of the presence of an abdominal mass. It is rare in North America and Western Europe but is one of the most common malignancies in parts of sub-Saharan Africa, Southeast Asia, East Asia, and elsewhere. A strong association seems to exist with chronic hepatitis B virus infection.
Hürthle cell carcinoma a malignant Hürthle cell tumor.
carcinoma in si´tu a neoplasm whose tumor cells are confined to the epithelium of origin, without invasion of the basement membrane; the likelihood of subsequent invasive growth is presumed to be high.
large cell carcinoma a type of bronchogenic carcinoma of undifferentiated (anaplastic) cells of large size, a variety of squamous cell carcinoma that has undergone further dedifferentiation.
medullary carcinoma that composed mainly of epithelial elements with little or no stroma.
mucinous carcinoma an adenocarcinoma that produces significant amounts of mucin.
nasopharyngeal carcinoma a malignant tumor arising in the epithelial lining of the nasopharynx, occurring at high frequency in people of Chinese descent. The epstein-barr virus has been implicated as a causative agent.
non–small cell carcinoma a general term comprising all lung carcinomas except small cell carcinoma, and including adenocarcinoma of the lung, large cell carcinoma, and squamous cell carcinoma.
oat cell carcinoma a form of small cell carcinoma in which the cells are round or elongated and slightly larger than lymphocytes; they have scanty cytoplasm and clump poorly.
papillary carcinoma carcinoma in which there are papillary growths that are irregular in nature arising from otherwise normal tissue; it can occur in the thyroid gland, the breast, or the bladder. Called also papillocarcinoma.
renal cell carcinoma carcinoma of the renal parenchyma, composed of tubular cells in varying arrangements; called also clear cell carcinoma.
scirrhous carcinoma carcinoma with a hard structure owing to the formation of dense connective tissue in the stroma. Called also fibrocarcinoma.
carcinoma sim´plex an undifferentiated carcinoma.
small cell carcinoma a common, highly malignant form of bronchogenic carcinoma in the wall of a major bronchus, occurring mainly in middle-aged individuals with a history of tobacco smoking; it is radiosensitive and has small oval undifferentiated cells. Metastasis to the hilum and to mediastinal lymph nodes is common.
spindle cell carcinoma squamous cell carcinoma marked by development of rapidly proliferating spindle cells.
squamous cell carcinoma
1. carcinoma developed from squamous epithelium, having cuboid cells and characterized by keratinization. Initially local and superficial, the lesion may later invade and metastasize.
2. the form occurring in the skin, usually originating in sun-damaged areas or preexisting lesions.
3. in the lung, one of the most common types of bronchogenic carcinoma, generally forming polypoid or sessile masses that obstruct the airways of the bronchi. It usually occurs in middle-aged individuals with a history of smoking. There is frequent invasion of blood and lymphatic vessels with metastasis to regional lymph nodes and other sites. Called also epidermoid carcinoma.
transitional cell carcinoma a malignant tumor arising from a transitional type of stratified epithelium, usually affecting the urinary bladder.
verrucous carcinoma
1. a variety of squamous cell carcinoma that has a predilection for the buccal mucosa but also affects other oral soft tissue and the larynx. It is slow-growing and somewhat invasive.
2. Buschke-Löwenstein tumor, so called because it is histologically similar to the oral lesion.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

mu·ci·nous car·ci·no·ma

a variety of adenocarcinoma in which the neoplastic cells secrete conspicuous quantities of mucin, and, as a result, the neoplasm is likely to be glistening, sticky, and gelatinoid in consistency.
Farlex Partner Medical Dictionary © Farlex 2012

mucinous carcinoma

A gelatinous subtype of secretory adenocarcinoma, in which clusters of tumour cells float in pools of pale mucin.

(1) Breast. A mucin-rich histologic variant type of carcinoma which may appear focally in other common invasive ductal and lobular carcinomas. Those carcinomas in which this is a predominant feature comprise less than 2% of all cases of breast carcinoma, and may have neuroendocrine features. Mucinous carcinoma occur in slightly older women, have a lower risk of nodal metastases, and a better prognosis—most deaths occur more than 12 years after initial diagnosis.

(2) Colon. A subtype of carcinoma with extracellular mucin—which contrasts to signet-ring carcinoma of the colon in that the mucin is intracellular; 5–15% of colorectal cancers are mucinous carcinomas, and have a slightly worse prognosis than more common colorectal adenocarcinomas.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.

mu·ci·nous car·ci·no·ma

(myū'si-nŭs kahr'si-nō'mă)
A variety of adenocarcinoma in which the neoplastic cells secrete conspicuous quantities of mucin; the neoplasms are glistening, sticky, and gelatinoid in consistency.
Synonym(s): colloid carcinoma.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

Mucinous (colloid) carcinoma

A type of cancer that accounts for 1% to 2% of breast cancers. Resembles medullary carcinoma in ultrasound and mammogram, but usually affects older women.
Mentioned in: Breast Ultrasound
Gale Encyclopedia of Medicine. Copyright 2008 The Gale Group, Inc. All rights reserved.
References in periodicals archive ?
The malignant lesions were 61 invasive ductal carcinomas, 9 invasive lobular carcinomas, 8 ductal carcinomas in situ, 3 invasive mucinous carcinomas, 1 invasive apocrine carcinoma, 1 medullary carcinoma, 1 medullary like carcinoma and 1 liposarcoma.
MacKay et al., "Mucinous carcinoma of the breast is genomically distinct from invasive ductal carcinomas of no special type," Journal of Pathology, vol.
Pure and mixed mucinous carcinomas of the breast: a clinicopathologic analysis of 61 cases with long-term follow-up.
Mucinous carcinoma of the breast: a pathologic study of 82 cases.
[35] Of the 268 malignant lesions, most common diagnosis was infiltrating duct carcinoma (N = 229), followed by medullary carcinoma (N = 2) and mucinous carcinoma, infiltrating lobular carcinoma, sarcomatoid carcinoma, invasive papillary carcinoma, and secretory carcinoma with one case each [Table 3].
In their study mucinous carcinoma occupied 3rd position constituting of 7 cases (15.21%).
The mean age of occurrence of mucinous carcinoma was 47.3 years (SD 7.1) and the median age was 45 years.
The final diagnoses of the lesions were as follows: PC (n = 109); acinar cell carcinoma (n = 2); inflammatory mass (n = 11); neuroendocrine tumor (NET) (n = 8); AIP (n = 9); invasive intraductal papillary mucinous carcinoma (IPMC) (n = 5); metastatic lesions (n = 2: lung cancer 1, melanoma 1); and intraductal tubular tumor (ITT) (n = 1) (Table 1).
The numerous black and white images in this atlas illustrate the size and location of ductal carcinoma in the breast, and the characteristics of invasive lobular carcinoma, mucinous carcinoma, medullary carcinoma, papillary carcinoma, inflammatory breast cancer, and benign lesions.
Jaffer, "Pleomorphic adenoma of the breast: a case report and distinction from mucinous carcinoma," Archives of Pathology and Laboratory Medicine, vol.
Clinicopathological variables Age (years) Mean 45.18 Tumor size (cm) [less than or 13 equal to] 2 cm 2-5 cm 18 >5 cm 5 Histopathological diagnosis IDC, NOS 29 Mucinous carcinoma 2 Metaplastic carcinoma 1 Medullary carcinoma 3 Mixed ductal-lobular carcinoma 1 Tumor necrosis Present 16 Absent 20 Margin Infiltrative 25 Pushing margin 11 Lymphocytic infiltrate Present 23 Absent 13 Tumor grade Grade I 5 Grade II 17 Grade III 14 Lymph node metastases Absent 12 1 to 3 14 >4 10 Tumour stage Stage I 5 Stage II 16 Stage III 13 Stage IV 2 Ki-67 Positive 29 Negative 7 Immunohistochemical panel CK5+ EGFR+ 22 CK5+ EGFR- 5 CK5- EGFR+ 9 CK5- EGFR- Nil TABLE 2: Correlation of EGFR and CK5 with clinicopathological variables.