mucinosis


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mucinosis

 [mu″si-no´sis]
a state with abnormal deposits of mucin in the skin, often associated with hypothyroidism (myxedema).
follicular mucinosis a disease of the pilosebaceous unit, presenting clinically as grouped follicular papules or plaques with associated hair loss, caused by mucinous infiltration of tissues, and usually involving the scalp, face, and neck. It may be primary (idiopathic), occurring most often in children, or it may be secondary to mycosis fungoides or reticulosis.

mu·ci·no·sis

(myū'si-nō'sis),
A condition in which mucin is present in the skin in excessive amounts, or in abnormal distribution; classified as: metabolic mucinosis, diffuse or pretibial myxedema, lichen myxedematosus, gargoylism; secondary mucinosis, degeneration in tumors; localized mucinosis, follicular, papular, plaquelike, focal, and myxoid or synovial cyst.
[mucin + G. -osis, condition]

mu·ci·no·sis

(myū'si-nō'sis)
A condition in which mucin is present in the skin in excessive amounts, or in abnormal distribution. Classified as metabolic mucinosis, secondary mucinosis, and localized mucinosis.
[mucin + G. -osis, condition]
References in periodicals archive ?
In this document, we present the case of a patient with generalized primary cutaneous mucinosis without any systemic disease.
Muto, "Adult variant of self-healing papular mucinosis in a patient with rheumatoid arthritis: Predominant proliferation of dermal dendritic cells expressing CD34 or factor XIIIa in association with dermal deposition of mucin," Journal of Dermatology, vol.
Shimizu, "Follicular mucinosis associated with imatinib (STI571)," British Journal of Dermatology, vol.
Another change observed is dermal mucinosis; cutaneous focal mucinosis is characterized by asymptomatic flesh-colored papules or nodules occurring on extremities.
Myxedema (cutaneous mucinosis) is a rare dermatological manifestation of hypothyroidism characterized by non-pitting thickening of the skin especially of the eyelids, cheeks and forehead and is associated with the deposition of hyaluronic acid in the dermis (Kelly and Hill, 1984).
Other changes noted in both the vessels and the tumor itself include vacuolization (Figure 14(c)), hyalinization (Figure 14(d)), mucinosis or myxoid change, and myocyte atypia or symplastic change, characterized by nuclear enlargement and hyperchromasia.
Differential diagnosis includes other inflammatory disorders of the scalp like tinea capitis, or a variant of folliculotropic mycosis fungoides with follicular mucinosis, and folliculitis decalvans, among other primary scarring alopecia.
Scleromyxedema (also called papular mucinosis) is a chronic connective tissue disorder in which mucin deposits cause the skin to become red and raised, and make the movement of affected areas difficult.
Less frequent reactions at injection sites include vascular thrombosis, mucinosis, dermal and SC sclerosis, necrosis, ulceration and rarely, lupus erythematosus-like lesions, sarcoidal granulomas, erythema nodosum, an acute septal panniculitis with neutrophils, lobular lymphocytic panniculitis and lipoatrophy.