23, 2015 /PRNewswire/ -- Medicines Development for Global Health (MDGH), an Australian not-for-profit biopharmaceutical company, has retained d3 Medicine through an innovative risk-share agreement to provide strategic advice on the development and regulatory strategy to support the registration of moxidectin
for onchocerciasis ("River Blindness").
It looked at 47 Welsh farms and the effectiveness of four types of wormer: Benzimidazole (1-BZ); Levamisole (2-LV); Ivermectin (3-ML) and Moxidectin
Some 94% of farms showed evidence of anthelmintic resistance to Benzimidazole, 68% to Levamisole, 51% to Ivermectin and 19% to Moxidectin
14) Other treatments include moxidectin
and benzyl benzoate.
The Global Health Investment Fund (GHIF) and Medicines Development for Global Health (Medicines Development) announced today a 10 million USD program for the registration of moxidectin
for the treatment of river blindness (onchocerciasis).
2) Macrocyclic Lactone injections (ivermectin, doramectin, moxidectin
etc) - these are popular, as they worm as well and are probably better in pregnant sheep (from the point of view of stress).
though looks promising in animal studies are still under development.
The main difference between these cat flea treatments is that Advantage only contains imidacloprid, whereas Advocate is a multi-purpose medication that combines imidacloprid with moxidectin
A recent example saw a farmer with triple resistance managing to maintain the production of lambs to slaughter for a few years by lowering stocking density, early lambing, creep feeding and treating with Moxidectin
on comparison the effect of pour on administration of Ivermectin, Doramectin, Eprinomectin and Moxidectin
shown that maximum and minimum effect was with Eprinomectin and Ivermectin observed respectively .
Cyathostomosis was suspected, so moxidectin
was administered twice, and prednisolone was given for 10 consecutive days.
The drug, moxidectin
, is being investigated for its potential to kill or sterilize the adult worms of Onchocerca volvulus, which cause onchocerciasis.