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the quantity of estrogen capable of producing in a spayed mouse a characteristic change in the vaginal epithelium, namely, disappearance of leukocytes and appearance of cornified cells, as determined by a vaginal smear; equal approximately to one half of an estrone unit.
Synonym(s): mouse unit
Farlex Partner Medical Dictionary © Farlex 2012
mouse unitAn obsolete, semi-quantitative bioassay unit corresponding to the amount of oestrogen required to produce characteristic microscopic changes in the vaginal epithelium of ovarectomise mice.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
Allen,Edgar, U.S. endocrinologist, 1892-1943.
Allen-Doisy test - a test for estrogenic activity.
Allen-Doisy unit - the quantity of estrogen capable of producing in a spayed mouse a characteristic change in the vaginal epithelium. Synonym(s): mouse unit
Medical Eponyms © Farlex 2012