Mitochondria are transported bidirectionally by interactions with molecular motor proteins
, such as kinesin-1 for anterograde movement and dynein for retrograde movement, and those attach via adaptor proteins such as the mitochondrial Rho-Milton complex and dynactin, respectively .
Myosin is a family of ATP-dependent motor proteins
and is mainly involved in muscle contraction.
Sperry (Department of Anatomy and Cell Biology, East Carolina University School of Medicine) presents protocols exploiting the functional and structural diversity of molecular motor proteins
, the proteins which produce energy for movement in cellular processes.
Myosins are a class of 40 motor proteins
that power cell movement and muscle contractions.
The spindle matrix protein NuMA, the centrosomal protein 4D2, and the spindle motor proteins
Kif2, KR[P.sub.110] and KR[P.sub.170] all localized to these structures.
The findings involve a class of DNA motor proteins
These include (1) the shuttling of electrons and protons across the inner fatty zones of bacterial cellular membranes by quinone molecules, a key step in the cells' energy-generating process; (2) the rotary action of several enzyme complexes; and (3) the movement along a track by certain motor proteins
, especially the kinesins.
Having created a gel that can replicate contractions, Saleh and Fygenson are now looking to refine their technique and enable distinct movements, such as twisting and crawling, or using other motor proteins
that would allow the gel to mimic other cell behaviors, such as shape-shifting and dividing.
Myosins are a family of ATP-dependent motor proteins
and are best known for their role in muscle contraction.
Coating those lines with so-called motor proteins
made microtubules scurry along the ridges.
Research into the activity of key motor proteins
suggests that a unique form of random motion powered by thermal energy may play a vital role in moving enzymes and other chemicals inside cells.