The electromotility of OHCs is produced by the motor protein
prestin, which is located on the lateral membrane.
Since it would be difficult to reconstitute flagellar motors from isolated motor proteins
, most work in this area employs intact cells with preassembled motors.
(1994) Purification of actin based motor protein
from Chara corallina.
Cytoplasmic dynein (CD) is a microtubule motor protein
responsible for multiple aspects of membrane transport and chromosomal segregation during mitosis.
These examples set the stage for a discussion of the motor protein
kinesin, which moves along protein tracks called microtubules.
MyoKardia presented preclinical data at the American Heart Association, or AHA, Scientific Sessions that demonstrated that targeting the heart's motor protein
, myosin, improved ventricular relaxation and compliance and normalized systolic function.
They identified the proteins, which include the motor protein
kinesin-2, and found that when these proteins were missing the microtubules no longer pointed the same way in dendrites; that is, their polarity became disorganized.
Further scans found that a motor protein
like those found in muscles piggybacked on GOLPH3.
Of particular note is the abundance of the microtubule-based motor protein
kinesin in the supernatant.
Using a bacterial motor protein
called FtsK50C, the scientists can cause the gel to react in the same way cytoskeletons react to the motor protein
myosin -- by contracting and stiffening.
In the study, the scientists found that a main driver of memory formation is myosin II, a motor protein
critical to cell movement and growth.
Among the cDNAs that were sequenced were ones with significant identities to KIF1A (5), a molecular motor involved in anterograde transport of synaptic vesicles (6), and to dynein light intermediate chain protein (DLIC-2), a constituent of the dynein motor protein