motor neuron disease


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motor

 [mo´ter]
1. pertaining to motion.
2. a muscle, nerve, or center that effects movements.

mo·tor neu·ron dis·ease (MND),

2. in the plural (that is, diseases) a generic term for a heterogenous group of disorders, all affecting motor neurons in the brain, spinal cord, or both, including spinal muscle atrophy, amyotrophic lateral sclerosis, progressive bulbar paralysis, and primary lateral sclerosis.

motor neuron disease

Neurology Any of a group of conditions characterized by progressive degeneration and dysfunction of the motor neuron or anterior horn cell–eg, amyotrophic lateral sclerosis–ALS; the terms are difficult to differentiate, and thus used interchangeably; the classic or sporadic form has an incidence rate of 2/105, characterized by upper limb weakness, atrophy, focal neurologic signs See Amyotrophic lateral sclerosis.

mo·tor neu·ron dis·ease

(mō'tŏr nūr'on di-zēz')
A general term comprising progressive spinal muscular atrophy (infantile, juvenile, and adult), amyotrophic lateral sclerosis, progressive bulbar paralysis, and primary lateral sclerosis; frequently a familial disease.

motor neuron disease

A rare disorder of unknown cause in which MOTOR nerve cells suffer gradual and progressive destruction. The condition is rare before the age of 40 and affects men twice as often as women. The initial symptoms depend on which neurons are first involved and include difficulty in swallowing and speaking, or wasting and weakness of the small muscles of the hands spreading to involve the forearms and later the legs. Progressive worsening leads to widespread paralysis of the whole body. Intellectual function is never affected. There is no known treatment. Also known as motor neurone disease.

mo·tor neu·ron dis·ease

(MND) (mō'tŏr nūr'on di-zēz')
2. In the plural (i.e., diseases) generic term for heterogenous group of disorders, all affecting motor neurons in the brain, spinal cord, or both.
References in periodicals archive ?
The Motor Neuron Disease Association points out that in the last five years the Government spent pounds 337,000 per diagnosed case of CJD as opposed to only pounds 108 per diagnosed case of motor neuron disease.
the epidemiology of motor neuron diseases: a review of recent studies.
About ALS (also called Motor Neuron Disease (MND), Charcot's disease or Lou Gehrig's disease)
"Establishing new neuromuscular connections over distances of a couple of centimetres in a young mouse is very different from attempting the same in human motor neuron diseases, especially in adults where the transplanted neurons may have to grow up to a metre to reach their target.
Alistair Purple, drop-in centre co-ordinator with The North East Motor Neuron Disease Trust, said: "We have to spend a lot of time fundraising so Trevor's efforts and the money raised are really significant.
Risk factors for motor neuron disease: a case-control study based on patients from the Scottish Motor Neuron Disease Register.
A breakthrough using cutting-edge stem cell research could speed up the discovery of new treatments for motor neuron disease (MND), a group of diseases that includes Lou Gehrig's disease (amyotrophic lateral sclerosis).
"The ability to create a range of different motor neurons is a key step in understanding the basis of selective subtype vulnerability in conditions such as motor neuron disease and spinal muscular atrophy."