motif


Also found in: Dictionary, Thesaurus, Legal, Acronyms, Encyclopedia, Wikipedia.

motif

(mō-tēf′)
n.
1.
a. A recurrent thematic element in an artistic or literary work.
b. A dominant theme or central idea.
2. Music A short rhythmic or melodic passage that is repeated or evoked in various parts of a composition.
3. A repeated figure or design in architecture or decoration.
4. A recurrent pattern either of molecular sequence, usually of nucleotides or amino acids in proteins, or of molecular structure that usually corresponds to specific biological activity.

motif

A short, conserved cluster of amino acids or nucleotides which share structural and usually functional similarity on a macromolecule; a 3-dimensional structure of gene product/protein with known or implied functions, often inferred from the cDNA sequence.

Protein motifs
DNA binding, leucine zipper, membrane spanning, zinc finger.

motif

(of a PROTEIN) a specific combination of SECONDARY STRUCTURES exhibiting a characteristic three-dimensional structure and often associated with a particular function. For example, the coiled-coil motif, comprising of two or more helices wound around each other. This is found in the GLYCOPROTEIN of EBOLA VIRUS and has a role in entry of the virus into host cells. Also the ZINC FINGER which comprises of an α helix and two β strands forming a finger-like structure held together by a zinc ion.

Patient discussion about motif

Q. What other illnesses are similar to asthma? I am 45 years old. My doctor suspects I might have adult asthma but there has yet been a final diagnosis made. What other problems might this be?

A. Before diagnosing someone as asthmatic, alternative possibilities should be considered. A clinician taking a history should check whether the patient is using any known bronchoconstrictors (substances that cause narrowing of the airways, e.g., certain anti-inflammatory agents or beta-blockers). Chronic obstructive pulmonary disease, which closely resembles asthma, is correlated with more exposure to cigarette smoke, an older patient, and decreased likelihood of family history of atopy. Your physician should examine these possibilities as well before diagnosing.

More discussions about motif
References in periodicals archive ?
Even between chimps and humans, whose genomes are 99 per cent identical, there are dozens of TFs which recognize diverse motifs between the two species in a way that would affect expression of hundreds of different genes.
It will be easier to compare them if we take into account the presence/absence of motifs such as these: A Living Creature Personifies Fire, Woman Gives Birth to Fire, First Fire is Stolen from Original Owner, Original Owner is a Jaguar, Original Owner is a Toad, etc.
The structure predication referred to the computational procedure for identifying template proteins from solved structure databases having similar structure or similar motif structure to the query protein sequence.
For the time being we are working on about 10 more motifs while new orders are still arriving.
Vary the number and/or size of lace motifs to adjust for other sizes.
Cyrus Parham, in his research, argued that the first manifestations of this ancient motif are in Scythian and Achaemenid art, mainly portrayed as the wings of Homa or Simurg , and which lasted in the same manner till the Sassanian period (224 - 651 A.D.)
Motif is a digital trust and safety services company serving e-commerce marketplaces, online retailers, travel agencies and financial services companies.
Understanding what one can do by manipulating positive and negative space is an important concept in making the motif for this assignment.
The overall results indicate that the carved panels with a floral motif are highly preferred, disregarding their function and placement in a house.
The first category simply views a CRM as a cluster of motif sites in windows and uses the set model to represent CRMs [4-9].
Use the existing fabric motif as a base for a unique design.
A number of geometrical shapes are constituted to create a single human motif. These isolated motifs carry one fold of rotational symmetry (7).