mosaicism
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Related to mosaicism: chimerism
mosaicism
[mo-za´ĭ-sizm]the presence in an individual of cells derived from the same zygote, but differing in chromosomal constitution.
mo·sa·i·cism
(mō-zā'i-sizm), [MIM*158250]Condition of being mosaic (2).
mosaicism
(mō-zā′ĭ-sĭz′əm)n.
A condition in which tissues of genetically different types occur in the same organism.
mosaicism
The phenotype of a multicelled organism, which is composed of cells expressing different genotypes; for instance, women are functionally mosaic due to the X chromosome genes expressed. Mosaicism due to mutation is less common.mo·sa·i·cism
(mō-zā'i-sizm)Condition of being mosaic (2).
mosaicism
The state in which two or more genetically different types of cell occur in the same individual. Although the cells are all derived from the same fertilized egg, they do not all possess the same number of chromosomes. In about 1% of cases of DOWN'S SYNDROME there are two different cell lines, one normal and the other with an additional chromosome 21 (trisomy 21). The effect of mosaicism varies with the proportion of cells containing abnormal chromosomes. Compare CHIMERA.Mosaicism
A genetic condition resulting from a mutation, crossing over, or nondisjunction of chromosomes during cell division, causing a variation in the number of chromosomes in the cells.
Mentioned in: Patau Syndrome