It is this gradient of morphogens
that tells stem cells what type of specialized cell and tissue to become.
With this model, it was possible to understand morphogen
's spatio-temporal dynamics and stationary concentration profiles during the process of cap formation from a semi-quantitative point of view.
Zhang et al., "Effects of morphogen
and scaffold porogen on the differentiation of dental pulp stem cells," Journal of Endodontics, vol.
are associated with MPs shed from the plasma membrane of apoptotic stimulated T cells.
Citation: "A microparticle approach to morphogen
delivery within pluripotent stem cell aggregates"; Andres M.
The research does not nix the theory - called the morphogen
theory - but science may now have a hypothetical tiger by the tail as they try to figure out this aspect of how Nature works.
A tissue-specific enhancer confers Pit-1-dependent morphogen
inducibility and autoregulation on the Pit-1 gene.
Although the detailed mechanism of STS action as a neurogenic morphogen
remains unclear, it seems that it is associated with the inhibition of some protein kinases which may contribute to neurite outgrowth .
Generation of a novel wing colour pattern by the Wingless morphogen
. Nature 464: 1143-1149.
Generation and interpretation of morphogen
It is likely that all-trans-retinoic acid (produced by cells from vitamin A) is a morphogen
and excess, or indeed treatment with a variety of retinoids, can potentially have disastrous effects on the developing fetus.
First, 5HT is a morphogen
in the developing mammalian central nervous system; perturbations of this system lead to errors in the architectural assembly of the brain (Hamon et al.