Early fetal heads, and major and minor salivary glands were collected retrospectively and glands were classified according to morphodifferentiation stage.
To evaluate immunohistochemical expression patterns, the major and minor salivary glands were classified according to the five morphodifferentiation stages (prebud, initial bud, pseudoglandular, canalicular, and terminal bud stages) described by Tucker.
Cobourne and Sharpe  described the possibility of dental abnormalities of the morphodifferentiation
type, both numeric and of form, but did not specify the incidence.
brevispora was identified as a fast-growing fungal species and could be considered a desirable material in morphodifferentiation
study and demonstration.
Histomorphometric examination has revealed that the talon cusp has normal enamel and dentin with a substantially enlarged pulp tissue, which suggests that talon tooth, may be a developmental anomaly originating in the stage of morphodifferentiation (10).
It is thought to occur during morphodifferentiation stage as a result of outward folding of inner enamel epithelial cells (precursors of ameloblasts) and transient focal hyperplasia of mesenchymal dental papilla (precursors of odontoblasts) or a combination of genetic and environmental factors (multifactorial) (2).
In multirooted teeth, morphodifferentiation
continues but the stimulating factors are not known yet.6 If during dental development the epithelial sheath of Hertwig is disrupted or folded, supernumerary roots and accessory root canals may be formed.
Many developing systems can be disturbed simultaneously by teratogenic influences which operate over a long period of morphodifferentiation
. But despite the fact that there are over 150 recognized disorders in which CL, CP or both may represent one feature, it is widely believed that the majority of affected individuals are otherwise structurally normal (rev by Jones, 1988).
The differential diagnosis of benign odontogenic tumors is based on a comparison of the degrees of tissue morphodifferentiation
Growth of the tooth germ proceeds after the appearance of the basal cell layer of the oral epithelium, and is followed by stages of proliferation, histodifferentiation, morphodifferentiation
, and final apposition to calcification.
This lesion takes place because, dental components are laid down in a disorganized manner, due to failure of normal morphodifferentiation
. Odontomas are of two types, the complex and the compound odontoma.
Conclusions: The fact that the talon cusp has normal enamel and dentine layers with a substantial enlarged pulp tissue suggests that talon tooth may be a developmental anomaly originating in the stage of morphodifferentiation