montelukast


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Related to montelukast: Montelukast sodium, Singulair

montelukast

 [mon″tĕ-loo´kast]
a leukotriene antagonist used as the sodium salt in prophylaxis and chronic treatment of asthma.

montelukast

(mŏn′tə-lo͞o′kăst)
n.
A drug that reduces the inflammatory response by acting as a leukotriene receptor antagonist, and is used to treat the signs and symptoms of asthma.

montelukast

Singulair® Internal medicine A leukotriene receptor antagonist used to manage asthma. See Asthma.

montelukast

A drug that binds to the receptors for certain leukotrienes thus blocking both phases of the ASTHMA response. It is used in the treatment of asthma that shows an inadequate response to inhaled steroids. A brand name is Singulair.

Montelukast (Singulair)

An inhibitor that prevents leukotrienes from binding to cell receptors; taken over time, montelukast can reduce or prevent symptoms of asthma and allergies.
References in periodicals archive ?
Group III: Montelukast (10): [MLT (10)]: OVA-sensitized and received standard drug treatment i.e.
From a theoretical point of view, when antihistamines and montelukast are concomitantly administered in AR, this combination would work better with greater efficacy, achieving good symptom control.
(TSX VENTURE:IGX)(OTCQX:IGXT), an oral drug delivery company, has received approval from Health Canada for the clinical trial application of its Montelukast VersaFilm, it was reported on Friday.
In fact, this event was attenuated by administration of the CysLTR-1 antagonist montelukast, but not by the CysLTR-2 specific antagonist Bay CysLT2 [51].
Material and Methods: Effects of variable doses of insulin (10-7-10-3 M) and insulin pretreated with salbutamol (10-6 M) and montelukast (10-5 M) were observed on airways of guinea pig in vitro by constructing cumulative dose response curves.
In our patient of CSU, the disease was there for last 15 years and not being controlled by regular use of antihistamines, montelukast and periodic intake of oral steroids.
PTZ was purchased from Sigma-Aldrich (USA), LTD4 and montelukast were from Cayman Chemical (USA), and phenobarbital was from Cristalia Pharmaceutical Co.
The approval and launch of the Montelukast Granules is part of an ever-growing portfolio that Ajanta Pharma has developed for the US market.
Patients in study group received 10mg of oral Montelukast and the control group received placebo.
Montelukast, a specific leukotriene receptor antagonist (LTRA), provides clinical benefit to patients with chronic asthma with a once-daily, oral administration.
Two others, montelukast and zafirlukast, were subsequently developed, receiving FDA approval in 1998 and 1999, respectively.