There were 127,762 and 127,186 SNVs present in each twin, respectively, and 124,185 (97.4%) of the SNVs were shared between the twins, supporting their monozygosity
. Twin 1 and twin 2 shared 79.7% of the total SNPs with their father and 80.0% with their mother, providing proof of the biological relationship of the family.
Research shows that the closest correlation to DNA test results on monozygosity
is the twins' own opinion, which was reported to be 95% correct.
When the data suggest monozygosity
, the noninvasive aneuploidy test could be applied, as long as the total fractional fetal DNA concentration exceeds the minimum stipulated by the test protocol, e.g., 4% (21).
Increasing birth length (P = 0.038), nonsmoking of the mother during pregnancy (P = 0.002), and monozygosity
(0.012) were also significant predictors for atopic dermatitis in the whole sample when ignoring the familial relationship between the twins (Table 1).
Al Mufti, "The Phenomenon of Monozygosity
: Spontaneous Zygotic Splitting," in Multiple Pregnancy: Epidemiology, Gestation, and Perinatal Outcome, 2nd ed., ed.
The phenomenon of monozygosity
in iatrogenic pregnancies.