Bivalent FMDO+PPR vaccine induced anti-FMDO-CFT and anti-PPR-VNT antibody response in the goats that was not significantly different from that of the goats vaccinated with either of monovalent vaccine
(Table 1 and 2).
Although the monovalent vaccine
is generally safe with a favourable benefit-risk ratio, it is associated with the potentially serious, albeit rare, adverse effect of intestinal intussusception.3 Intussusception refers to intestinal obstruction caused by telescoping of a bowel segment into its adjacent distal segment, and is the commonest cause of acute abdomen in children.
Rotarix is a monovalent vaccine
of rotavirus strain G1P8 attenuated in Vero cell culture.
When they vaccinated mice with either the bivalent or monovalent vaccine
(both with genetically identical human HA proteins), they found equal immune responses across the board.
Odds ratio (OR) and 95% confidence intervals (95% CI) were also evaluated for the LB risk in vaccinated people at the initial and final dose schedules as well as the overall protection following vaccination with the monovalent vaccine
The hepatitis B monovalent vaccine
can be administered together with oral polio and BCG.
Use of influenza A (H1N1) 2009 monovalent vaccine
: recommendations of the Advisory Committee on Immunization Practices (ACIP), 2009.
Yih and her associates also looked at data from 103,098 doses of a monovalent vaccine
, GlaxoSmithKline's RV1 (Rotarix).
Low coverage is connected to insufficient allocation of financial resources to purchase enough preventive monovalent vaccine
. Coverage in 1994 was - 15.7%, in 1995 - 7.6% and in 2001 - 0.01%.
A separate study assessed intussusception cases recorded within 7 days after a first or second dose of the monovalent vaccine
Initially, sera from chickens vaccinated with a monovalent vaccine
(H5N2) or from turkeys naturally infected during an H7N3 influenza outbreak were tested by pseudotype neutralization assay (pp-NT) assay using the "monoplex" format and serological results were compared to the standard reference HI test.