G undergoes a Monospot test
, which is positive, with subsequent evidence of a prior, but not active, Epstein-Barr virus (EBV) infection.
Initial laboratory investigation performed in the emergency department revealed a mild elevation of liver function enzymes and a negative Monospot test
. In addition, testing for viral hepatitis A, B and C was also negative.
A rapid antigen detection test for streptococcal pharyngitis ("rapid strep" test) and monospot test
were both negative.
A monospot test
was positive for the presence of heterophile antibodies and further serological testing was carried out which detected the presence of IgM and IgG antibodies to the Epstein-Barr viral capsid antigen (VCA).
Blood cultures, monospot test
(a form of the heterophile antibody test for infectious mononucleosis due to Epstein-Barr virus), and serology for hepatitis viruses were all negative.
The patients often have a positive immunoglobulin M monospot test
, which is more sensitive but less specific.
and strep screen were negative and complete blood count with differential was normal.
COLORADO SPRINGS -- "When you're running a Monospot test
, when you're thinking viral meningitis, you also should be thinking acute HIM" according to Dr.
An EBV-specific antibody panel is the next step in the persistently ill patient with a negative monospot test
. It not only nails down the diagnosis but also can tell us where the patient is in the course of infection.
He had absolute lymphocytosis (lymphocyte count: 12.24 x [10.sup.9]/L), a positive Monospot test
, and an elevated liver enzyme level.
The Paul-Bunnell or Monospot test
detects heterophile antibodies, which bind to red blood cells of other species (sheep or horse, respectively).
Serologic tests for infectious hepatitis A, B, C, and brucella, and a Monospot test