monogenic


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Related to monogenic: monogenic disease

mon·o·gen·ic

(mon'ō-jen'ik),
Relating to a hereditary disease or syndrome, or to an inherited characteristic, controlled by alleles at a single genetic locus.

monogenic

(mŏn′ə-jĕn′ĭk)
adj.
1. Of or regulated by one gene or one of a pair of allelic genes.
2.
a. Of or relating to monogenesis; monogenetic.
b. Of or relating to monogenism.

mon′o·gen′i·cal·ly adv.

monogenic

adjective Referring to:
(1) A trait or protein controlled by or associated with a single gene;
(2) An inherited condition or characteristic controlled by alleles at a single genetic locus.

mon·o·gen·ic

(mon'ō-jen'ik)
Relating to a hereditary disease or syndrome, or to an inherited characteristic, controlled by alleles at a single genetic locus.

monogenic

of or relating to an inherited characteristic that is controlled by one gene.

mon·o·gen·ic

(mon'ō-jen'ik)
Relating to a hereditary disease or syndrome, or to an inherited characteristic.
References in periodicals archive ?
Riesz transform is a two-dimensional extension of the Hilbert transform [9], The monogenic signal based on Riesz transform can convert the one-dimensional signal into two-dimensional signal.
These mice show severe insulin deficiency and have a short lifespan; however, caution should be used in extrapolating findings from a monogenic model in a rodent to a more complex polygenic disease in humans, as the pathophysiologies are likely to be different.
Hattersley, "Clinical implications of a molecular genetic classification of monogenic beta-cell diabetes," Nature Clinical Practice Endocrinology & Metabolism, vol.
Monogenic diabetes is often misdiagnosed as either type 1 or 2 diabetes, and as such patients are often treated inappropriately.
Monogenic hypercholesterolemia: new insights in pathogenesis and treatment.
5) that describe the genotype and phenotype probabilities for monogenic Mendelian inheritance.
1) The genetic basis of monogenic autoinflammatory diseases (MAD) and the importance of genetic diagnosis
Most diseases are multifactorial (even when monogenic), therefore monotherapy is reaching its limits as can be witnessed by the very high number of failures in late phase development.
Mutations in some of the genes highlighted are also known to be associated with severe monogenic syndromes-conditions caused by a single genetic mutations-characterised by compromised muscle function.
Most rare diseases are genetic and include congenital abnormalities in growth, chromosomal monogenic syndromes, skeletal malformations, hereditary metabolic diseases, and hereditary cancers.
One should emphasize the association of FMF as a monogenic autoinfammatory disease, and coexistent H.
The researchers have a particular interest in finding new treatments for genetic forms of diseases like monogenic diabetes and Hirschsprung's disease.